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Mammalian Phenotype (MP): abnormal spleen white pulp morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + 3:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + 3:   abnormal immune system morphology [MP:0000685] <3>(50|76) (60|35|18)
+ + 2:   abnormal immune system organ morphology [MP:0002722] <8>(21|31) (26|15|9)
+ + 2:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(57|86) (66|47|21)
+ 1:   abnormal spleen morphology [MP:0000689] <16>(10|15) (12|8|8)
0:   abnormal spleen white pulp morphology [MP:0002357] <10>(6|8) (6|6|3)
- 1:   abnormal spleen B cell follicle morphology [MP:0008470] <3>(4|6) (4|4|2)
- 1:   abnormal spleen marginal zone morphology [MP:0002362] <3>(2|1) (2|2|1)
- 1:   abnormal metallophilic macrophage morphology [MP:0008241](0|0) (0|0|0)
- 1:   abnormal spleen central arteriole morphology [MP:0002361](0|0) (0|0|0)
- 1:   abnormal spleen marginal sinus morphology [MP:0002363](0|0) (0|0|0)
- 1:   abnormal spleen periarteriolar lymphoid sheath morphology [MP:0002358](0|0) (0|0|0)
- 1:   absent spleen white pulp [MP:0005046](0|0) (0|0|0)
- 1:   decreased spleen white pulp amount [MP:0008479](0|0) (0|0|0)
- 1:   increased spleen white pulp amount [MP:0008478](0|0) (0|0|0)
- 1:   intermingled spleen red and white pulp [MP:0008475](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
TNF receptor-like0.0000000001192Direct
WWE domain0.001442Inherited
SH2 domain0.004663Inherited
Caspase-like0.009773Inherited
TNF-like0.02018Inherited
DEATH domain0.06425Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
TNF receptor-like0.000000003447Direct
WWE domain0.0005051Direct
Interferon regulatory factor 3 (IRF3), transactivation domain0.0009882Direct
SH2 domain0.003525Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.01113Inherited
TNF-like0.01512Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.02193Inherited
DEATH domain, DD0.0279Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
TNF receptor-like0.00000000004355Direct
WWE domain0.000807Direct
SH2 domain0.002778Inherited
Caspase-like0.006094Inherited
TNF-like0.01325Inherited
DEATH domain0.0466Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.00000001204Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0000000697Direct
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0001817Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.01973Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.05432Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0000003883Direct
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.000165Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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