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Mammalian Phenotype (MP): altered susceptibility to autoimmune disorder

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   mammalian phenotype [MP:0000001] <29>
+ + + + + 5:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + 4:   abnormal immune system physiology [MP:0001790] <16>(59|84) (66|49|28)
+ + + 3:   abnormal immune tolerance [MP:0005000] <3>(11|19) (13|8|1)
+ + 2:   abnormal self tolerance [MP:0005005] <1>(11|19) (13|8|1)
+ 1:   autoimmune response [MP:0001844] <4>(11|19) (13|8|1)
0:   altered susceptibility to autoimmune disorder [MP:0002425] <2>(2|9) (3|4|1)
- 1:   decreased susceptibility to autoimmune disorder [MP:0005351] <9>(1|7) (2|3|0)
- 1:   increased susceptibility to autoimmune disorder [MP:0005350] <9>(1|1) (1|1|1)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
MHC antigen-recognition domain0.0009941Direct
TNF receptor-like0.6476Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Interleukin 17F, IL-17F0.00000261Direct
C1 set domains (antibody constant domain-like)0.0001291Direct
Long-chain cytokines0.0001463Direct
Interleukin-1 (IL-1)0.0001844Direct
MHC antigen-recognition domain0.0008009Direct
C2 set domains0.002398Inherited
Papain-like0.008652Inherited
TNF receptor-like0.3365Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.538Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
MHC antigen-recognition domain0.0005426Direct
p53-like transcription factors0.32Inherited
TNF receptor-like0.604Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.0002092Direct
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001142Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.4436Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.5227Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.5227Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)