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Mammalian Phenotype (MP): abnormal CD4-positive, alpha beta T cell morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + + + 9:   mammalian phenotype [MP:0000001] <29>
+ + + + + + + + 8:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + + + + + 8:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + + + + 7:   abnormal immune system morphology [MP:0000685] <3>(50|76) (60|35|18)
+ + + + + + + 7:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(57|86) (66|47|21)
+ + + + + + 6:   abnormal hematopoietic cell morphology [MP:0013656] <9>(48|77) (60|43|18)
+ + + + + + 6:   abnormal immune system cell morphology [MP:0000716] <5>(37|63) (48|29|16)
+ + + + + 5:   abnormal leukocyte morphology [MP:0008246] <4>(36|62) (47|29|15)
+ + + + 4:   abnormal mononuclear cell morphology [MP:0008247] <2>(33|57) (41|28|14)
+ + + 3:   abnormal lymphocyte morphology [MP:0002619] <5>(27|46) (33|26|14)
+ + 2:   abnormal T cell morphology [MP:0008037] <9>(14|25) (18|19|11)
+ 1:   abnormal effector T cell morphology [MP:0002435] <7>(7|16) (8|13|6)
+ 1:   abnormal alpha-beta T cell morphology [MP:0012762] <13>(7|17) (8|14|6)
0:   abnormal CD4-positive, alpha beta T cell morphology [MP:0002432] <6>(3|11) (4|10|4)
- 1:   abnormal CD4-positive, alpha beta T cell number [MP:0008073] <9>(1|8) (2|7|2)
- 1:   abnormal CD4-positive helper T cell morphology [MP:0010183] <4>(0|1) (0|0|0)
- 1:   abnormal CD4-positive T cell differentiation [MP:0008076] <3>(0|3) (2|3|2)
- 1:   abnormal CD4-positive, alpha-beta memory T cell morphology [MP:0010834] <2>(0|0) (0|0|0)
- 1:   abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology [MP:0008397] <1>(0|0) (0|0|0)
- 1:   abnormal CD4-positive, alpha-beta intraepithelial T cell morphology [MP:0008400](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
STAT0.0000001533Direct
Transcription factor STAT-4 N-domain0.0000001533Direct
Integrin domains0.005507Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
STAT DNA-binding domain0.00000009005Direct
STAT0.00000009005Direct
Transcription factor STAT-4 N-domain0.00000009005Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.000004107Direct
Phoshoinositide 3-kinase (PI3K) helical domain0.0002144Direct
Integrin domains0.004051Inherited
TNF receptor-like0.01132Inherited
Interleukin 17F, IL-17F0.2354Inherited
V set domains (antibody variable domain-like)0.5181Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.5805Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.6705Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
STAT0.00000006086Direct
Transcription factor STAT-4 N-domain0.00000006086Direct
Integrin domains0.003313Inherited
TNF receptor-like0.02214Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.00000006086Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.00000006086Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.00000006086Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.0001762Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0007332Direct
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.001427Inherited
    53300,69318
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 0.004589Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.2262Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.3048Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.6578Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.00000006086Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.00000006086Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0001762Direct
    53300,69318,69179
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.004589Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)