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Mammalian Phenotype (MP): abnormal immunoglobulin level

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + + 5:   abnormal hematopoietic system physiology [MP:0001545] <5>(39|53) (40|38|21)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   abnormal blood cell physiology [MP:0012382] <3>(38|53) (39|38|21)
+ + + 3:   abnormal adaptive immunity [MP:0002420] <8>(36|48) (38|33|21)
+ + + 3:   abnormal leukocyte physiology [MP:0002442] <5>(34|48) (36|33|20)
+ + + 3:   abnormal immune cell physiology [MP:0001819] <3>(35|48) (37|33|21)
+ + + 3:   abnormal cell-mediated immunity [MP:0002421] <3>(35|48) (37|33|21)
+ + + 3:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + 2:   abnormal professional antigen presenting cell physiology [MP:0002452] <3>(25|32) (26|19|12)
+ + 2:   abnormal lymphocyte physiology [MP:0003945] <4>(21|31) (23|22|13)
+ + 2:   abnormal immune system physiology [MP:0001790] <16>(59|84) (66|49|28)
+ 1:   abnormal immune serum protein physiology [MP:0002723] <4>(25|40) (31|24|12)
+ 1:   abnormal B cell physiology [MP:0002459] <9>(19|27) (20|16|10)
+ 1:   abnormal humoral immune response [MP:0001800] <4>(10|14) (12|10|8)
0:   abnormal immunoglobulin level [MP:0002490] <7>(8|12) (9|9|7)
- 1:   abnormal IgG level [MP:0020174] <5>(6|11) (7|7|6)
- 1:   decreased immunoglobulin level [MP:0002460] <5>(2|5) (2|4|2)
- 1:   increased immunoglobulin level [MP:0002461] <5>(2|6) (2|1|1)
- 1:   abnormal IgA level [MP:0020171] <2>(0|0) (0|0|0)
- 1:   abnormal IgD level [MP:0020172] <2>(0|0) (0|0|0)
- 1:   abnormal IgE level [MP:0020173] <2>(2|1) (2|0|0)
- 1:   abnormal IgM level [MP:0020180] <2>(1|0) (1|2|1)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
L30e-like0.008558Inherited
TNF receptor-like0.00923Inherited
TNF-like0.03312Inherited
p53-like transcription factors0.05469Inherited
Bcl-2 inhibitors of programmed cell death0.07334Inherited
4-helical cytokines0.203Inherited
Toll/Interleukin receptor TIR domain0.3245Inherited
Family A G protein-coupled receptor-like0.5555Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Rel/Dorsal transcription factors, DNA-binding domain0.000000005558Direct
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.00000002839Direct
TNF receptor-like0.01736Inherited
Short-chain cytokines0.01882Inherited
TNF-like0.0238Inherited
Bcl-2 inhibitors of programmed cell death0.05604Inherited
DEATH domain, DD0.144Inherited
Interleukin 17F, IL-17F0.2327Inherited
C1 set domains (antibody constant domain-like)0.2802Inherited
V set domains (antibody variable domain-like)0.3397Inherited
Toll/Interleukin receptor TIR domain0.3589Inherited
I set domains0.4228Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
L30e-like0.005291Inherited
TNF receptor-like0.005729Inherited
TNF-like0.02267Inherited
p53-like transcription factors0.03895Inherited
Bcl-2 inhibitors of programmed cell death0.05384Inherited
4-helical cytokines0.166Inherited
Toll/Interleukin receptor TIR domain0.2802Inherited
DEATH domain0.357Inherited
Family A G protein-coupled receptor-like0.5087Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.000000003232Direct
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.00007496Direct
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.001654Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.04441Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.05384Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.05428Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.05571Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.1423Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50729,50044,55550
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0Direct
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.0001869Direct
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0001869Direct
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.05384Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.1862Inherited
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.2275Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)