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Mammalian Phenotype (MP): abnormal semilunar valve morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   cardiovascular system phenotype [MP:0005385] <2>(67|85) (77|57|35)
+ + + 3:   abnormal cardiovascular system morphology [MP:0002127] <7>(48|65) (53|44|33)
+ + 2:   abnormal heart morphology [MP:0000266] <22>(27|44) (28|25|19)
+ 1:   abnormal heart valve morphology [MP:0000285] <9>(4|5) (4|3|0)
0:   abnormal semilunar valve morphology [MP:0002746] <2>(2|3) (2|3|0)
- 1:   abnormal aortic valve morphology [MP:0002747] <9>(1|2) (1|2|0)
- 1:   abnormal pulmonary valve morphology [MP:0002748] <9>(2|3) (2|2|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Blood coagulation inhibitor (disintegrin)0.000001343Direct
Orange domain-like0.00001478Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Blood coagulation inhibitor (disintegrin)0.0000009044Direct
Hairy Orange domain0.000009247Direct
Reprolysin-like0.111Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Blood coagulation inhibitor (disintegrin)0.0000005503Direct
Orange domain-like0.000006568Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.0000005503Direct
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.000006568Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.1631Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)