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Mammalian Phenotype (MP): abnormal somatic nervous system morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   nervous system phenotype [MP:0003631] <2>(98|128) (113|79|50)
+ 1:   abnormal nervous system morphology [MP:0003632] <17>(76|104) (91|64|47)
0:   abnormal somatic nervous system morphology [MP:0002752] <7>(34|47) (37|25|14)
- 1:   abnormal cranial nerve morphology [MP:0001056] <12>(6|9) (7|6|2)
- 1:   abnormal cranial ganglia morphology [MP:0001081] <7>(1|3) (4|1|0)
- 1:   abnormal somatic sensory system morphology [MP:0000959] <4>(26|38) (29|19|12)
- 1:   abnormal spinal nerve morphology [MP:0001077] <4>(3|3) (3|1|0)
- 1:   abnormal common peroneal nerve morphology [MP:0011211] <1>(0|0) (0|0|0)
- 1:   abnormal somatic motor system morphology [MP:0001051] <1>(1|3) (1|3|2)
- 1:   abnormal brachial plexus formation [MP:0013915](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Tubby C-terminal domain-like0Direct
Lamin A/C globular tail domain0Direct
Homeodomain-like0.000003861Direct
GDNF receptor-like0.002036Inherited
Growth factor receptor domain0.003778Inherited
EGF/Laminin0.01488Inherited
Nuclear receptor ligand-binding domain0.02486Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.03437Inherited
Sema domain0.06133Inherited
lambda repressor-like DNA-binding domains0.06611Inherited
GAF domain-like0.07134Inherited
Cystine-knot cytokines0.07692Inherited
Intermediate filament protein, coiled coil region0.07893Inherited
Plexin repeat0.08157Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.09048Inherited
Nicotinic receptor ligand binding domain-like0.09048Inherited
Cadherin-like0.138Inherited
Orange domain-like0.1658Inherited
Clc chloride channel0.1658Inherited
Notch domain0.1658Inherited
HLH, helix-loop-helix DNA-binding domain0.2285Inherited
Integrin domains0.2621Inherited
Family A G protein-coupled receptor-like0.2644Inherited
Frizzled cysteine-rich domain0.2706Inherited
CBS-domain pair0.2709Inherited
HD-domain/PDEase-like0.2842Inherited
Spectrin repeat0.2851Inherited
HMG-box0.3647Inherited
E2F-DP heterodimerization region0.3793Inherited
Second domain of FERM0.3979Inherited
beta-beta-alpha zinc fingers0.666Inherited
Cyclin-like0.7944Inherited
SH3-domain0.8125Inherited
PDZ domain-like0.8303Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Neurotrophin0Direct
Transcriptional factor tubby, C-terminal domain0Direct
Retinoblastoma tumor suppressor domains0Direct
Lamin A/C globular tail domain0Direct
Homeodomain0.0000002305Direct
L domain0.0001722Direct
GDNF receptor-like0.001444Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.002264Inherited
Laminin-type module0.009272Inherited
Adenylyl and guanylyl cyclase catalytic domain0.01579Inherited
Nuclear receptor ligand-binding domain0.02025Inherited
Nuclear receptor0.02025Inherited
Paired domain0.04058Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.04058Inherited
POU-specific domain0.04847Inherited
Sema domain0.05107Inherited
Growth factor receptor domain0.05107Inherited
GAF domain0.05676Inherited
Plexin repeat0.06977Inherited
Intermediate filament protein, coiled coil region0.07377Inherited
Nicotinic receptor ligand binding domain-like0.07701Inherited
Extracellular domain of cell surface receptors0.07701Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.07701Inherited
EGF-type module0.07803Inherited
Hairy Orange domain0.1416Inherited
Notch domain0.1416Inherited
DIX domain0.1416Inherited
Clc chloride channel0.1416Inherited
cAMP-binding domain0.1448Inherited
DEP domain0.1467Inherited
Cadherin0.175Inherited
Calmodulin-like0.176Inherited
Rhodopsin-like0.2126Inherited
PDEase0.2166Inherited
HLH, helix-loop-helix DNA-binding domain0.217Inherited
Spectrin repeat0.2286Inherited
CBS-domain pair0.2427Inherited
E2F dimerization segment0.2427Inherited
Frizzled cysteine-rich domain0.2471Inherited
Integrin domains0.2498Inherited
HMG-box0.3408Inherited
Cell cycle transcription factor e2f-dp0.351Inherited
EF-hand modules in multidomain proteins0.4557Inherited
PDZ domain0.4855Inherited
Classic zinc finger, C2H20.5146Inherited
Motor proteins0.5735Inherited
SH3-domain0.8094Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Lamin A/C globular tail domain0Direct
Tubby C-terminal domain-like0Direct
Homeodomain-like0.000001644Direct
GDNF receptor-like0.001158Inherited
Growth factor receptor domain0.002217Inherited
EGF/Laminin0.009543Inherited
Nucleotide cyclase0.01214Inherited
Nuclear receptor ligand-binding domain0.01661Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.0236Inherited
Sema domain0.04423Inherited
lambda repressor-like DNA-binding domains0.04806Inherited
GAF domain-like0.05226Inherited
Cystine-knot cytokines0.05662Inherited
Intermediate filament protein, coiled coil region0.05819Inherited
Plexin repeat0.06032Inherited
Nicotinic receptor ligand binding domain-like0.0676Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.0676Inherited
Cadherin-like0.1083Inherited
Clc chloride channel0.1324Inherited
Notch domain0.1324Inherited
Orange domain-like0.1324Inherited
L domain-like0.162Inherited
HLH, helix-loop-helix DNA-binding domain0.1897Inherited
Integrin domains0.2209Inherited
Family A G protein-coupled receptor-like0.2231Inherited
Frizzled cysteine-rich domain0.2291Inherited
CBS-domain pair0.2293Inherited
HD-domain/PDEase-like0.2418Inherited
Spectrin repeat0.2426Inherited
HMG-box0.319Inherited
E2F-DP heterodimerization region0.3332Inherited
Second domain of FERM0.3513Inherited
beta-beta-alpha zinc fingers0.6234Inherited
"Winged helix" DNA-binding domain0.7165Inherited
Cyclin-like0.7593Inherited
SH3-domain0.7785Inherited
PDZ domain-like0.7977Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.0001255Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.0001255Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.00172Inherited
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0.001927Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.005403Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.02153Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.04423Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.04681Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.04681Inherited
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.05226Inherited
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.05226Inherited
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.05226Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.0676Inherited
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.07055Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.08017Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.08017Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.1324Inherited
    47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.1324Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.2291Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.3332Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.3899Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.5285Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.5322Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.5712Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.0001255Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0006752Direct
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.02415Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0365Inherited
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.05226Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.07055Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.08017Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.08017Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.1221Inherited
    47473,47473,57850
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.1324Inherited
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1361Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.2741Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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