SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Mammalian Phenotype (MP): colitis

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   mammalian phenotype [MP:0000001] <29>
+ + + + + + 6:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + + 5:   abnormal immune system physiology [MP:0001790] <16>(59|84) (66|49|28)
+ + + + + 5:   digestive/alimentary phenotype [MP:0005381] <2>(38|46) (40|19|9)
+ + + + 4:   abnormal inflammatory response [MP:0001845] <4>(27|38) (29|18|5)
+ + + + 4:   abnormal digestive system physiology [MP:0001663] <18>(16|16) (17|7|5)
+ + + 3:   increased inflammatory response [MP:0001846] <35>(23|35) (25|17|4)
+ + + 3:   abnormal intestine physiology [MP:0010155] <4>(9|10) (9|6|4)
+ + 2:   intestinal inflammation [MP:0001858] <2>(8|9) (8|3|2)
+ 1:   large intestinal inflammation [MP:0003304] <3>(8|9) (8|3|2)
0:   colitis [MP:0002816] <1>(6|7) (6|3|2)
- 1:   abnormal susceptibility to induced colitis [MP:0013296] <3>(3|7) (3|1|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
N-acetylmuramoyl-L-alanine amidase-like0Direct
Toll/Interleukin receptor TIR domain0.000000418Direct
RNI-like0.0001282Direct
4-helical cytokines0.0002035Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0008326Direct
Riboflavin synthase domain-like0.0008326Direct


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
N-acetylmuramoyl-L-alanine amidase-like0Direct
Interleukin 17F, IL-17F0.0000001408Direct
Pyrin domain, PYD0.000002371Direct
Toll/Interleukin receptor TIR domain0.000006363Direct
28-residue LRR0.000232Direct
Interferons/interleukin-10 (IL-10)0.0003263Direct
Caspase recruitment domain, CARD0.002665Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
N-acetylmuramoyl-L-alanine amidase-like0Direct
Toll/Interleukin receptor TIR domain0.0000001686Direct
RNI-like0.00006325Direct
4-helical cytokines0.000103Direct
Riboflavin synthase domain-like0.0004504Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0004504Direct

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00000284Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0001244Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0006213Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.00001227Direct
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.00001227Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)