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Mammalian Phenotype (MP): joint inflammation

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + 3:   abnormal immune system physiology [MP:0001790] <16>(59|84) (66|49|28)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   abnormal inflammatory response [MP:0001845] <4>(27|38) (29|18|5)
+ + 2:   skeleton phenotype [MP:0005390] <2>(46|63) (50|41|26)
+ 1:   increased inflammatory response [MP:0001846] <35>(23|35) (25|17|4)
+ 1:   abnormal skeleton physiology [MP:0001533] <12>(17|20) (18|12|6)
0:   joint inflammation [MP:0002933] <4>(6|6) (6|5|0)
- 1:   arthritis [MP:0002993] <4>(5|5) (5|4|0)
- 1:   decreased susceptibility to induced joint inflammation [MP:0003079] <1>(1|1) (1|0|0)
- 1:   acute joint inflammation [MP:0002934](0|0) (0|0|0)
- 1:   chronic joint inflammation [MP:0002935](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
TNF-like0.004125Inherited
Kringle-like0.008909Inherited
PGBD-like0.01225Inherited
Hemopexin-like domain0.01225Inherited
Toll/Interleukin receptor TIR domain0.1173Inherited
Growth factor receptor domain0.4637Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
TNF-like0.003385Inherited
Hemopexin-like domain0.009886Inherited
MMP N-terminal domain0.009886Inherited
Matrix metalloproteases, catalytic domain0.009886Inherited
Ngr ectodomain-like0.06863Inherited
Toll/Interleukin receptor TIR domain0.08407Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
TNF-like0.002437Inherited
Kringle-like0.005517Inherited
Hemopexin-like domain0.007763Inherited
PGBD-like0.007763Inherited
Toll/Interleukin receptor TIR domain0.09033Inherited
Growth factor receptor domain0.416Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.0005303Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0008303Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.007763Inherited
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.009644Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.009644Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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