SUPERFAMILY 1.75 HMM library and genome assignments server

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Mammalian Phenotype (MP): arthritis

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   mammalian phenotype [MP:0000001] <29>
+ + + + + 5:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + 4:   abnormal immune system physiology [MP:0001790] <16>(59|84) (66|49|28)
+ + + 3:   abnormal inflammatory response [MP:0001845] <4>(27|38) (29|18|5)
+ + + 3:   skeleton phenotype [MP:0005390] <2>(46|63) (50|41|26)
+ + 2:   abnormal skeleton physiology [MP:0001533] <12>(17|20) (18|12|6)
+ + 2:   increased inflammatory response [MP:0001846] <35>(23|35) (25|17|4)
+ 1:   joint inflammation [MP:0002933] <4>(6|6) (6|5|0)
0:   arthritis [MP:0002993] <4>(5|5) (5|4|0)
- 1:   decreased susceptibility to induced arthritis [MP:0003436](0|0) (0|0|0)
- 1:   increased susceptibility to induced arthritis [MP:0003724](0|0) (0|0|0)
- 1:   osteoarthritis [MP:0003560](1|1) (1|0|0)
- 1:   rheumatoid arthritis [MP:0003561](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Kringle-like0.00005147Direct
TNF-like0.00007549Direct
PGBD-like0.000269Direct
Hemopexin-like domain0.0005263Direct
Growth factor receptor domain0.1012Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
TNF-like0.0000674Direct
MMP N-terminal domain0.0002172Direct
Matrix metalloproteases, catalytic domain0.0002773Direct
Hemopexin-like domain0.0004333Direct
Ngr ectodomain-like0.03288Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Kringle-like0.00002423Direct
TNF-like0.0000361Direct
PGBD-like0.0001376Direct
Hemopexin-like domain0.0002787Direct
Growth factor receptor domain0.07645Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.000001612Direct
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.00002112Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.00008093Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.0001376Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)