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Mammalian Phenotype (MP): large intestinal inflammation

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   mammalian phenotype [MP:0000001] <29>
+ + + + + 5:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + 4:   digestive/alimentary phenotype [MP:0005381] <2>(38|46) (40|19|9)
+ + + + 4:   abnormal immune system physiology [MP:0001790] <16>(59|84) (66|49|28)
+ + + 3:   abnormal inflammatory response [MP:0001845] <4>(27|38) (29|18|5)
+ + + 3:   abnormal digestive system physiology [MP:0001663] <18>(16|16) (17|7|5)
+ + 2:   increased inflammatory response [MP:0001846] <35>(23|35) (25|17|4)
+ + 2:   abnormal intestine physiology [MP:0010155] <4>(9|10) (9|6|4)
+ 1:   intestinal inflammation [MP:0001858] <2>(8|9) (8|3|2)
0:   large intestinal inflammation [MP:0003304] <3>(8|9) (8|3|2)
- 1:   colitis [MP:0002816] <1>(6|7) (6|3|2)
- 1:   cecum inflammation [MP:0009481](0|0) (0|0|0)
- 1:   proctitis [MP:0003305](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
N-acetylmuramoyl-L-alanine amidase-like0Direct
DEATH domain0.0000003557Direct
Toll/Interleukin receptor TIR domain0.0000006206Direct
RNI-like0.0001772Direct
Nuclear receptor ligand-binding domain0.0008832Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0009824Direct
Riboflavin synthase domain-like0.0009824Direct
4-helical cytokines0.8236Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
N-acetylmuramoyl-L-alanine amidase-like0Direct
Interleukin 17F, IL-17F0.0000001825Direct
Pyrin domain, PYD0.000003019Direct
Toll/Interleukin receptor TIR domain0.00000887Direct
28-residue LRR0.0002901Direct
Nuclear receptor0.0007488Direct
Nuclear receptor ligand-binding domain0.0009511Direct
Caspase recruitment domain, CARD0.003154Inherited
Interferons/interleukin-10 (IL-10)0.5296Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
N-acetylmuramoyl-L-alanine amidase-like0Direct
DEATH domain0.0000001431Direct
Toll/Interleukin receptor TIR domain0.0000002503Direct
RNI-like0.00008897Direct
Nuclear receptor ligand-binding domain0.0004781Direct
Riboflavin synthase domain-like0.0005356Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0005356Direct
4-helical cytokines0.7904Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000003617Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0001492Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0007394Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0000149Direct
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0000149Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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