SUPERFAMILY 1.75 HMM library and genome assignments server

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Mammalian Phenotype (MP): abnormal tumor morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   neoplasm [MP:0002006] <2>(32|37) (38|18|7)
+ 1:   altered tumor pathology [MP:0010639] <4>(9|11) (10|8|5)
0:   abnormal tumor morphology [MP:0003448] <3>(5|5) (5|4|2)
- 1:   decreased tumor growth/size [MP:0003447](3|3) (3|2|1)
- 1:   increased tumor growth/size [MP:0003721](0|0) (0|0|0)
- 1:   osseous metaplasia [MP:0010347](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Integrin beta tail domain0.0002864Direct
Metalloproteases ("zincins"), catalytic domain0.0003194Direct
PGBD-like0.001016Inherited
Hemopexin-like domain0.001912Inherited
Kringle-like0.002299Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Matrix metalloproteases, catalytic domain0.00008606Direct
Integrin beta tail domain0.000191Direct
Integrin beta EGF-like domains0.0003367Direct
MMP N-terminal domain0.0007318Direct
Hemopexin-like domain0.001423Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Integrin beta tail domain0.0001469Direct
Metalloproteases ("zincins"), catalytic domain0.0001653Direct
PGBD-like0.0005554Direct
Hemopexin-like domain0.001085Inherited
Kringle-like0.001314Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0.0001469Direct
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.0001469Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0002625Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.0005554Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.00002728Direct
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.0001469Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)