SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Mammalian Phenotype (MP): nervous system phenotype

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   mammalian phenotype [MP:0000001] <29>
0:   nervous system phenotype [MP:0003631] <2>(98|128) (113|79|50)
- 1:   abnormal nervous system physiology [MP:0003633] <38>(43|60) (52|31|18)
- 1:   abnormal nervous system morphology [MP:0003632] <17>(76|104) (91|64|47)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Composite domain of metallo-dependent hydrolases0Direct
Metallothionein0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Proton glutamate symport protein0Direct
Tubby C-terminal domain-like0Direct
E2F-DP heterodimerization region0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Synuclein0Direct
Hedgehog/DD-peptidase0Direct
Hedgehog/intein (Hint) domain0Direct
Lamin A/C globular tail domain0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
Notch domain0Direct
Homeodomain-like0.0000000000008705Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0000000003588Direct
Nicotinic receptor ligand binding domain-like0.0000000003588Direct
Periplasmic binding protein-like I0.00000002852Direct
PDZ domain-like0.00000341Direct
HLH, helix-loop-helix DNA-binding domain0.00002439Direct
Voltage-gated potassium channels0.00003887Direct
Spectrin repeat0.0001248Direct
Periplasmic binding protein-like II0.0001259Direct
Nuclear receptor ligand-binding domain0.0002279Direct
NHL repeat0.0003405Direct
Sema domain0.0003676Direct
Frizzled cysteine-rich domain0.0005281Direct
Plexin repeat0.0005589Direct
Galactose-binding domain-like0.001578Inherited
L27 domain0.001741Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.005392Inherited
Family A G protein-coupled receptor-like0.005558Inherited
Fibronectin type III0.00753Inherited
Orange domain-like0.00832Inherited
Caspase-like0.01072Inherited
YWTD domain0.0132Inherited
GAF domain-like0.01752Inherited
EGF/Laminin0.02282Inherited
Concanavalin A-like lectins/glucanases0.02393Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.02473Inherited
p53-like transcription factors0.027Inherited
SMAD MH1 domain0.02868Inherited
Cupredoxins0.04282Inherited
SNF-like0.04282Inherited
Doublecortin (DC)0.05372Inherited
HCP-like0.05372Inherited
SH3-domain0.05965Inherited
Metallo-dependent hydrolases0.06746Inherited
Riboflavin synthase domain-like0.06746Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.06746Inherited
SRF-like0.07335Inherited
GDNF receptor-like0.07335Inherited
HMA, heavy metal-associated domain0.07335Inherited
Growth factor receptor domain0.08636Inherited
lambda repressor-like DNA-binding domains0.08697Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.1066Inherited
Clc chloride channel0.1066Inherited
GTPase activation domain, GAP0.1177Inherited
TIMP-like0.1295Inherited
PH domain-like0.1546Inherited
Cysteine-rich domain0.1666Inherited
Kringle-like0.1679Inherited
Cystine-knot cytokines0.1682Inherited
L domain-like0.1702Inherited
Bcl-2 inhibitors of programmed cell death0.1727Inherited
Cap-Gly domain0.1749Inherited
Flavoproteins0.1749Inherited
Cadherin-like0.1898Inherited
SNARE fusion complex0.1911Inherited
cAMP-binding domain-like0.1947Inherited
4-helical cytokines0.237Inherited
Cyclin-like0.239Inherited
Zn-dependent exopeptidases0.2599Inherited
Immunoglobulin0.2599Inherited
Formate/glycerate dehydrogenase catalytic domain-like0.2766Inherited
CBS-domain pair0.3016Inherited
Second domain of FERM0.3119Inherited
Integrin domains0.4386Inherited
SAM/Pointed domain0.4815Inherited
Spermadhesin, CUB domain0.4875Inherited
PLP-dependent transferases0.5056Inherited
MFS general substrate transporter0.5266Inherited
HD-domain/PDEase-like0.5442Inherited
BAR/IMD domain-like0.5735Inherited
HMG-box0.6039Inherited
TNF receptor-like0.6055Inherited
Toll/Interleukin receptor TIR domain0.6217Inherited
Bromodomain0.6471Inherited
PreATP-grasp domain0.6708Inherited
Intermediate filament protein, coiled coil region0.7143Inherited
Complement control module/SCR domain0.7397Inherited
FAD/NAD(P)-binding domain0.773Inherited
ABC transporter transmembrane region0.8399Inherited
Glutathione synthetase ATP-binding domain-like0.8774Inherited
SAP domain0.8903Inherited
beta-beta-alpha zinc fingers0.9352Inherited
alpha/beta-Hydrolases0.9748Inherited
RNA-binding domain, RBD0.9999Inherited
Cysteine proteinases1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Hedgehog (development protein), N-terminal signaling domain0Direct
Lamin A/C globular tail domain0Direct
Proton glutamate symport protein0Direct
Transcriptional factor tubby, C-terminal domain0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Notch domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Hedgehog C-terminal (Hog) autoprocessing domain0Direct
Other IPT/TIG domains0Direct
Hydantoinase (dihydropyrimidinase)0Direct
Synapsin C-terminal domain0Direct
Neurotrophin0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
Hydantoinase (dihydropyrimidinase), catalytic domain0Direct
Metallothionein0Direct
E2F dimerization segment0Direct
Retinoblastoma tumor suppressor domains0Direct
Synuclein0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Synapsin domain0Direct
Homeodomain0.000000000002318Direct
Nicotinic receptor ligand binding domain-like0.0000000004052Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0000000004052Direct
L-arabinose binding protein-like0.0000006887Direct
Laminin G-like module0.000001364Direct
Phosphate binding protein-like0.00000503Direct
PDZ domain0.00002349Direct
HLH, helix-loop-helix DNA-binding domain0.00003363Direct
Nuclear receptor0.00006464Direct
Nuclear receptor ligand-binding domain0.0002256Direct
Sema domain0.0003228Direct
Frizzled cysteine-rich domain0.0004267Direct
Plexin repeat0.0005163Direct
Spectrin repeat0.0007532Direct
Laminin-type module0.0008421Direct
L27 domain0.001299Inherited
Hypoxia-inducible factor Hif2a, C-terminal domain0.002294Inherited
DEP domain0.002919Inherited
Caspase catalytic domain0.002919Inherited
Rhodopsin-like0.002932Inherited
Voltage-gated potassium channels0.004647Inherited
Hairy Orange domain0.00639Inherited
Ephrin ectodomain0.00639Inherited
Fibronectin type III0.01017Inherited
YWTD domain0.01098Inherited
Paired domain0.01197Inherited
Cell cycle transcription factor e2f-dp0.01197Inherited
DIX domain0.01376Inherited
GAF domain0.01376Inherited
I set domains0.01609Inherited
LDL receptor-like module0.02321Inherited
SMAD MH1 domain0.02339Inherited
SMAD domain0.02339Inherited
NADPH-cytochrome p450 reductase-like0.02909Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.02909Inherited
Extracellular domain of cell surface receptors0.02986Inherited
Enabled/VASP homology 1 domain (EVH1 domain)0.02986Inherited
SNF-like0.03699Inherited
cAMP-binding domain0.03745Inherited
L domain0.04467Inherited
Doublecortin (DC)0.04467Inherited
Formate/glycerate dehydrogenases, substrate-binding domain0.06073Inherited
beta-glycanases0.06073Inherited
GDNF receptor-like0.06073Inherited
Mib/herc2 domain0.06073Inherited
Multidrug efflux transporter AcrB transmembrane domain0.06073Inherited
SRF-like0.06073Inherited
HMA, heavy metal-associated domain0.06073Inherited
SH3-domain0.07406Inherited
Pyridoxal-dependent decarboxylase0.08333Inherited
Clc chloride channel0.0934Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.0934Inherited
Ephrin receptor ligand binding domain0.09716Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.09716Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.09758Inherited
Phosphotyrosine-binding domain (PTB)0.09873Inherited
Forkhead DNA-binding domain0.1048Inherited
Ngr ectodomain-like0.1198Inherited
EGF-type module0.1275Inherited
EF-hand modules in multidomain proteins0.1343Inherited
POU-specific domain0.1343Inherited
Bcl-2 inhibitors of programmed cell death0.1566Inherited
Cap-Gly domain0.1571Inherited
SNARE fusion complex0.1808Inherited
Tetramerization domain of potassium channels0.1808Inherited
Cadherin0.2023Inherited
Long-chain cytokines0.2046Inherited
Motor proteins0.2086Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.2157Inherited
CBS-domain pair0.2174Inherited
Calmodulin-like0.2186Inherited
Synaptotagmin-like (S variant)0.23Inherited
Fibronectin type II module0.2306Inherited
Adenylyl and guanylyl cyclase catalytic domain0.2323Inherited
SAM (sterile alpha motif) domain0.2377Inherited
Formate/glycerate dehydrogenases, NAD-domain0.2559Inherited
Leucine zipper domain0.2831Inherited
Transforming growth factor (TGF)-beta0.2946Inherited
Acetylcholinesterase-like0.3111Inherited
PLC-like (P variant)0.3141Inherited
FYVE, a phosphatidylinositol-3-phosphate binding domain0.3627Inherited
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.3666Inherited
Cyclin0.3739Inherited
Cytoplasmic domain of inward rectifier potassium channel0.3941Inherited
Growth factor receptor domain0.3946Inherited
PDEase0.4046Inherited
p120GAP domain-like0.4307Inherited
Integrin domains0.4365Inherited
Actin/HSP700.4384Inherited
C1 set domains (antibody constant domain-like)0.4384Inherited
Integrin alpha N-terminal domain0.4384Inherited
Spermadhesin, CUB domain0.4969Inherited
TNF receptor-like0.5111Inherited
HMG-box0.6139Inherited
Bromodomain0.6504Inherited
G proteins0.6882Inherited
Toll/Interleukin receptor TIR domain0.7126Inherited
Intermediate filament protein, coiled coil region0.7235Inherited
Complement control module/SCR domain0.7462Inherited
BAR domain0.7468Inherited
ABC transporter transmembrane region0.8399Inherited
MAM domain0.8859Inherited
SAP domain0.8859Inherited
Classic zinc finger, C2H20.9004Inherited
SH2 domain0.9022Inherited
ABC transporter ATPase domain-like0.9153Inherited
Canonical RBD0.9695Inherited
V set domains (antibody variable domain-like)1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Tubby C-terminal domain-like0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Synuclein0Direct
Hedgehog/intein (Hint) domain0Direct
Metallothionein0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
Proton glutamate symport protein0Direct
Notch domain0Direct
Hedgehog/DD-peptidase0Direct
Lamin A/C globular tail domain0Direct
Composite domain of metallo-dependent hydrolases0Direct
E2F-DP heterodimerization region0Direct
Homeodomain-like0.0000000000003159Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0000000001318Direct
Nicotinic receptor ligand binding domain-like0.0000000001318Direct
Periplasmic binding protein-like I0.00000001092Direct
PDZ domain-like0.000001447Direct
HLH, helix-loop-helix DNA-binding domain0.0000111Direct
Voltage-gated potassium channels0.00001802Direct
Spectrin repeat0.00006149Direct
Periplasmic binding protein-like II0.00006205Direct
Nuclear receptor ligand-binding domain0.0001155Direct
NHL repeat0.000177Direct
Sema domain0.0001913Direct
Frizzled cysteine-rich domain0.0002799Direct
Plexin repeat0.0002967Direct
Galactose-binding domain-like0.0008855Direct
L27 domain0.0009832Direct
Glucocorticoid receptor-like (DNA-binding domain)0.00324Inherited
Family A G protein-coupled receptor-like0.003344Inherited
Fibronectin type III0.004617Inherited
Orange domain-like0.005136Inherited
Caspase-like0.00673Inherited
YWTD domain0.008399Inherited
GAF domain-like0.0114Inherited
EGF/Laminin0.01513Inherited
Concanavalin A-like lectins/glucanases0.01593Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.01651Inherited
LDL receptor-like module0.01653Inherited
p53-like transcription factors0.01815Inherited
SMAD MH1 domain0.0194Inherited
SNF-like0.02989Inherited
Cupredoxins0.02989Inherited
Doublecortin (DC)0.03817Inherited
HCP-like0.03817Inherited
E set domains0.04255Inherited
SH3-domain0.04292Inherited
Metallo-dependent hydrolases0.04914Inherited
Riboflavin synthase domain-like0.04914Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.04914Inherited
SRF-like0.05384Inherited
HMA, heavy metal-associated domain0.05384Inherited
GDNF receptor-like0.05384Inherited
Mib/herc2 domain-like0.05384Inherited
Growth factor receptor domain0.06426Inherited
lambda repressor-like DNA-binding domains0.06474Inherited
Glutamine synthetase/guanido kinase0.07313Inherited
Multidrug efflux transporter AcrB transmembrane domain0.08107Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.08107Inherited
Clc chloride channel0.08107Inherited
GTPase activation domain, GAP0.09063Inherited
TIMP-like0.1007Inherited
PH domain-like0.1229Inherited
Cysteine-rich domain0.1332Inherited
Kringle-like0.1343Inherited
Cystine-knot cytokines0.1345Inherited
L domain-like0.1363Inherited
Bcl-2 inhibitors of programmed cell death0.1386Inherited
Cap-Gly domain0.1405Inherited
Flavoproteins0.1405Inherited
Cadherin-like0.1541Inherited
SNARE fusion complex0.1553Inherited
cAMP-binding domain-like0.1585Inherited
BRCT domain0.1727Inherited
4-helical cytokines0.1976Inherited
Cyclin-like0.1995Inherited
Nucleotide cyclase0.2021Inherited
Zn-dependent exopeptidases0.2189Inherited
Immunoglobulin0.2189Inherited
Leucine zipper domain0.2332Inherited
Formate/glycerate dehydrogenase catalytic domain-like0.2347Inherited
CBS-domain pair0.2583Inherited
Second domain of FERM0.2681Inherited
"Winged helix" DNA-binding domain0.303Inherited
ARM repeat0.3241Inherited
Quinoprotein alcohol dehydrogenase-like0.3289Inherited
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.3399Inherited
Integrin domains0.3911Inherited
TPR-like0.4027Inherited
Integrin alpha N-terminal domain0.4232Inherited
SAM/Pointed domain0.4338Inherited
Spermadhesin, CUB domain0.4399Inherited
PLP-dependent transferases0.458Inherited
MFS general substrate transporter0.4793Inherited
HD-domain/PDEase-like0.4974Inherited
BAR/IMD domain-like0.5271Inherited
HMG-box0.5583Inherited
TNF receptor-like0.5601Inherited
Toll/Interleukin receptor TIR domain0.5768Inherited
Bromodomain0.6036Inherited
PreATP-grasp domain0.6285Inherited
Intermediate filament protein, coiled coil region0.6744Inherited
Complement control module/SCR domain0.7011Inherited
FAD/NAD(P)-binding domain0.736Inherited
ABC transporter transmembrane region0.808Inherited
Glutathione synthetase ATP-binding domain-like0.8486Inherited
SH2 domain0.8523Inherited
SAP domain0.8626Inherited
beta-beta-alpha zinc fingers0.9119Inherited
alpha/beta-Hydrolases0.9567Inherited
RNA-binding domain, RBD0.987Inherited
Cysteine proteinases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55166,51294
  • 55166 - Hedgehog/DD-peptidase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0Direct
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0Direct
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    57196,56496
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 0Direct
    57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0Direct
    81296,101898
  • 81296 - E set domains
  • 101898 - NHL repeat
  • 0Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0Direct
    46966,51045
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0Direct
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0Direct
    49562,51045
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 51045 - WW domain
  • 0Direct
    50729,50156
  • 50729 - PH domain-like
  • 50156 - PDZ domain-like
  • 0Direct
    81324,53850
  • 81324 - Voltage-gated potassium channels
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    49785,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    51045,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0Direct
    56496,49899
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0Direct
    48726,82895
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.0000000001318Direct
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.00001159Direct
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0001592Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.0001913Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.0001913Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.000222Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0002799Direct
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.0009832Direct
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.005136Inherited
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.005136Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.006123Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.009618Inherited
    53822,53850
  • 53822 - Periplasmic binding protein-like I
  • 53850 - Periplasmic binding protein-like II
  • 0.0114Inherited
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.0114Inherited
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.0114Inherited
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.0114Inherited
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.0114Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.01715Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0194Inherited
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.02511Inherited
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.02511Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.03109Inherited
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.03817Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.03817Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.03817Inherited
    89837,89837
  • 89837 - Doublecortin (DC)
  • 89837 - Doublecortin (DC)
  • 0.03817Inherited
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.03817Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.04893Inherited
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.04914Inherited
    48452,81901
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 0.05384Inherited
    57535,49854
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 0.05384Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.0577Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.07198Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.07198Inherited
    81324,81324
  • 81324 - Voltage-gated potassium channels
  • 81324 - Voltage-gated potassium channels
  • 0.08107Inherited
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.08156Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.08374Inherited
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0.1405Inherited
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.1405Inherited
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.1928Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.2126Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.2156Inherited
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.2347Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.3352Inherited
    49854,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0.3399Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.3608Inherited
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 0.3608Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.3705Inherited
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.4323Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.4323Inherited
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.5365Inherited
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.5406Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.8069Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.808Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.8414Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.8736Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    63411,63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0Direct
    101288,50156,50044
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    56496,49899,49899
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    49785,49899,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    57196,56496,49899
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    46966,51045,47473
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0Direct
    75399,75399,75399
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 0Direct
    51045,47473,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0Direct
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    48726,82895,82895
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    49503,49503,49503
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 0Direct
    50729,50156,50156
  • 50729 - PH domain-like
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0Direct
    46966,46966,51045
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0Direct
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    47473,47473,57850
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0Direct
    49899,57196,56496
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 0Direct
    48726,48726,82895
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    49899,49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.0004072Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0004139Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0004661Direct
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.002193Inherited
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.002263Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0034Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.0034Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.003926Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.00442Inherited
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.0114Inherited
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.0114Inherited
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.0114Inherited
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.0114Inherited
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.02511Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.03817Inherited
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.04914Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0507Inherited
    57535,49854,57535
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0.05384Inherited
    49854,57535,49854
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 0.05384Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.1337Inherited
    49854,57535,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.2347Inherited
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.3003Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.3324Inherited
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.4323Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.6058Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.665Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.972Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)