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Mammalian Phenotype (MP): abnormal male reproductive system physiology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   reproductive system phenotype [MP:0005389] <2>(38|58) (47|18|6)
+ 1:   abnormal reproductive system physiology [MP:0001919] <10>(21|39) (27|11|2)
0:   abnormal male reproductive system physiology [MP:0003698] <12>(4|8) (4|4|0)
- 1:   abnormal sperm physiology [MP:0004543] <3>(0|0) (0|0|0)
- 1:   abnormal testis physiology [MP:0004884] <3>(0|0) (0|0|0)
- 1:   abnormal penile erection [MP:0001379] <2>(0|0) (0|0|0)
- 1:   abnormal ejaculation [MP:0001378] <1>(0|0) (0|0|0)
- 1:   abnormal epididymis physiology [MP:0014190] <1>(0|0) (0|0|0)
- 1:   abnormal male germ cell apoptosis [MP:0008280] <1>(1|2) (1|0|0)
- 1:   abnormal prostate gland physiology [MP:0003607] <1>(0|0) (0|1|0)
- 1:   abnormal seminal vesicle physiology [MP:0013902] <1>(0|0) (0|0|0)
- 1:   abnormal bulbourethral gland physiology [MP:0011781](0|0) (0|0|0)
- 1:   male infertility [MP:0001925](2|5) (2|2|0)
- 1:   penis inflammation [MP:0013143](0|0) (0|0|0)
- 1:   reduced male fertility [MP:0001922](0|0) (0|1|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
PAZ domain0.000501Direct
The spindle assembly checkpoint protein mad20.001618Inherited
E2F-DP heterodimerization region0.002501Inherited
Nucleic acid-binding proteins0.01554Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Gonadodropin/Follitropin0.0001386Direct
PAZ domain0.0002838Direct
E2F dimerization segment0.0005858Direct
The spindle assembly checkpoint protein mad20.0009707Direct
DNA gyrase/MutL, second domain0.0009707Direct
DNA gyrase/MutL, N-terminal domain0.0009707Direct
Single strand DNA-binding domain, SSB0.001534Inherited
Tudor domain0.2483Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
PAZ domain0.0002649Direct
The spindle assembly checkpoint protein mad20.0009099Direct
E2F-DP heterodimerization region0.001438Inherited
Nucleic acid-binding proteins0.01Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.001438Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.003189Inherited
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0.02081Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.3549Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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