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Mammalian Phenotype (MP): abnormal female reproductive system physiology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   reproductive system phenotype [MP:0005389] <2>(38|58) (47|18|6)
+ 1:   abnormal reproductive system physiology [MP:0001919] <10>(21|39) (27|11|2)
0:   abnormal female reproductive system physiology [MP:0003699] <13>(10|24) (17|6|2)
- 1:   abnormal pregnancy [MP:0009661] <6>(3|3) (4|0|0)
- 1:   abnormal uterus physiology [MP:0009671] <5>(0|0) (0|0|0)
- 1:   abnormal ovary physiology [MP:0003507] <4>(1|2) (2|0|0)
- 1:   abnormal oviduct physiology [MP:0012018] <3>(0|0) (0|0|0)
- 1:   abnormal ovulation [MP:0001928] <3>(0|0) (0|0|0)
- 1:   abnormal gestational length [MP:0002292] <2>(0|1) (1|0|0)
- 1:   abnormal ovulation cycle [MP:0009344] <2>(2|2) (3|1|0)
- 1:   abnormal miscarriage rate [MP:0004244](0|0) (0|0|0)
- 1:   female infertility [MP:0001926](0|2) (0|0|0)
- 1:   impaired luteinization [MP:0003356](0|0) (0|0|0)
- 1:   increased granulosa cell apoptosis [MP:0013508](1|2) (2|1|0)
- 1:   miscarriage [MP:0013172](0|0) (0|0|0)
- 1:   reduced female fertility [MP:0001923](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
4-helical cytokines0.0001519Direct
HMA, heavy metal-associated domain0.0007652Direct
PYP-like sensor domain (PAS domain)0.0008187Direct
Alpha-macroglobulin receptor domain0.01022Inherited
Nuclear receptor ligand-binding domain0.01474Inherited
Terpenoid cyclases/Protein prenyltransferases0.03238Inherited
Fibronectin type III0.2122Inherited
EGF/Laminin0.587Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
Retinoblastoma tumor suppressor domains0Direct
PAS domain of steroid receptor coactivator 1A, NCo-A10Direct
p53 tetramerization domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Short-chain cytokines0.00003302Direct
Gonadodropin/Follitropin0.00006243Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.00006243Direct
NADPH-cytochrome p450 reductase-like0.00006243Direct
Neurotrophin0.0005269Direct
HMA, heavy metal-associated domain0.0005269Direct
Long-chain cytokines0.00058Direct
STAT DNA-binding domain0.0007318Direct
STAT0.0007318Direct
Transcription factor STAT-4 N-domain0.0007318Direct
Nuclear receptor0.003834Inherited
Complement components0.007998Inherited
Alpha-macroglobulin receptor domain0.007998Inherited
Nuclear receptor ligand-binding domain0.01427Inherited
EGF-type module0.1321Inherited
Ngr ectodomain-like0.1937Inherited
Fibronectin type III0.2318Inherited
I set domains0.5523Inherited


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
p53 tetramerization domain0Direct
4-helical cytokines0.00007584Direct
HMA, heavy metal-associated domain0.0004112Direct
PYP-like sensor domain (PAS domain)0.0004424Direct
Flavoproteins0.0005507Direct
STAT0.0005507Direct
Transcription factor STAT-4 N-domain0.0005507Direct
Glucocorticoid receptor-like (DNA-binding domain)0.005207Inherited
Alpha-macroglobulin receptor domain0.006398Inherited
Nuclear receptor ligand-binding domain0.009462Inherited
Terpenoid cyclases/Protein prenyltransferases0.02213Inherited
Fibronectin type III0.1745Inherited
L domain-like0.3506Inherited
Family A G protein-coupled receptor-like0.4706Inherited
EGF/Laminin0.5409Inherited
Immunoglobulin0.9342Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.0002125Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0005507Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.0005507Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0005507Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.527Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0005507Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0005507Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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