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Mammalian Phenotype (MP): abnormal facial morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   growth/size/body region phenotype [MP:0005378] <12>(64|95) (71|47|27)
+ + 2:   craniofacial phenotype [MP:0005382] <1>(20|36) (24|17|10)
+ 1:   abnormal craniofacial morphology [MP:0000428] <5>(20|36) (24|17|10)
+ 1:   abnormal head morphology [MP:0000432] <8>(12|23) (14|5|2)
0:   abnormal facial morphology [MP:0003743] <10>(8|18) (8|3|2)
- 1:   abnormal mouth morphology [MP:0000452] <13>(6|13) (6|1|2)
- 1:   abnormal nose morphology [MP:0002233] <9>(2|2) (2|0|0)
- 1:   abnormal snout morphology [MP:0000443] <9>(0|0) (0|0|0)
- 1:   abnormal paranasal sinus morphology [MP:0002240] <4>(0|0) (0|0|0)
- 1:   facial cleft [MP:0008797] <3>(0|0) (1|0|0)
- 1:   increased facial tumor incidence [MP:0008018] <3>(0|0) (0|0|0)
- 1:   flat face [MP:0012175](0|0) (0|0|0)
- 1:   midface hypoplasia [MP:0012085](0|1) (0|0|0)
- 1:   taut facial appearance [MP:0000437](0|0) (0|0|0)
- 1:   triangular face [MP:0012546](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
Cystine-knot cytokines0.001319Inherited
p53-like transcription factors0.2747Inherited
TB module/8-cys domain0.3024Inherited
Homeodomain-like0.3759Inherited
Intermediate filament protein, coiled coil region0.3781Inherited
FnI-like domain0.804Inherited
Family A G protein-coupled receptor-like0.9603Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
Retinoblastoma tumor suppressor domains0Direct
p53 tetramerization domain0Direct
Multidrug efflux transporter AcrB transmembrane domain0.0005366Direct
Pyridoxal-dependent decarboxylase0.004388Inherited
Extracellular domain of cell surface receptors0.004773Inherited
Ephrin ectodomain0.008128Inherited
Transforming growth factor (TGF)-beta0.01221Inherited
I set domains0.03726Inherited
Laminin-type module0.09964Inherited
DEATH domain, DD0.1387Inherited
VWC domain0.1936Inherited
T-box0.2471Inherited
TB module/8-cys domain0.2696Inherited
Homeodomain0.2747Inherited
Intermediate filament protein, coiled coil region0.349Inherited
Paired domain0.6002Inherited
Rhodopsin-like0.9115Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
Cystine-knot cytokines0.0007335Direct
p53-like transcription factors0.2329Inherited
TB module/8-cys domain0.259Inherited
Homeodomain-like0.33Inherited
Intermediate filament protein, coiled coil region0.332Inherited
FnI-like domain0.7694Inherited
Family A G protein-coupled receptor-like0.9402Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    46579,64593
  • 46579 - Prefoldin
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.0004321Direct
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.1847Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.0005844Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.01465Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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