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Mammalian Phenotype (MP): abnormal nephron morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   renal/urinary system phenotype [MP:0005367] <2>(41|47) (46|26|11)
+ + 2:   abnormal renal/urinary system morphology [MP:0000516] <14>(31|36) (36|22|11)
+ 1:   abnormal kidney morphology [MP:0002135] <29>(26|28) (28|15|6)
0:   abnormal nephron morphology [MP:0003881] <8>(19|22) (21|12|3)
- 1:   abnormal renal tubule morphology [MP:0002703] <11>(8|9) (9|4|0)
- 1:   abnormal renal corpuscle morphology [MP:0002827] <6>(10|15) (12|9|3)
- 1:   abnormal nephron morphogenesis [MP:0012024] <2>(0|0) (0|0|0)
- 1:   abnormal nephron number [MP:0011289] <1>(2|1) (2|0|0)
- 1:   absent nephron [MP:0011292](0|0) (0|0|0)
- 1:   dilated nephron [MP:0011293](0|0) (0|0|0)
- 1:   nephron necrosis [MP:0011291](0|0) (0|0|0)
- 1:   renal cast [MP:0011402](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Families 57/38 glycoside transferase middle domain0.00002029Direct
Glycoside hydrolase/deacetylase0.00009229Direct
Galactose mutarotase-like0.000252Direct
HCP-like0.003706Inherited
L30e-like0.006075Inherited
Bcl-2 inhibitors of programmed cell death0.009157Inherited
Nuclear receptor ligand-binding domain0.06211Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.1222Inherited
TNF receptor-like0.1278Inherited
Sema domain0.1278Inherited
Plexin repeat0.2178Inherited
(Trans)glycosidases0.23Inherited
C-type lectin-like0.2329Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.2564Inherited
Riboflavin synthase domain-like0.2564Inherited
Flavoproteins0.2564Inherited
Integrin domains0.4818Inherited
Cystine-knot cytokines0.5599Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
alpha-mannosidase, domain 20.00001336Direct
alpha-mannosidase0.00001336Direct
alpha-mannosidase, C-terminal domain0.0001626Direct
Bcl-2 inhibitors of programmed cell death0.00712Inherited
Short-chain cytokines0.02337Inherited
Nuclear receptor ligand-binding domain0.05431Inherited
Nuclear receptor0.05431Inherited
Sema domain0.1148Inherited
Leucine zipper domain0.1431Inherited
TNF receptor-like0.1654Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain0.1654Inherited
Plexin repeat0.206Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.2371Inherited
Noncollagenous (NC1) domain of collagen IV0.2371Inherited
NADPH-cytochrome p450 reductase-like0.2371Inherited
Cytochrome p450 reductase N-terminal domain-like0.2371Inherited
VWC domain0.3598Inherited
Laminin-type module0.3598Inherited
Transforming growth factor (TGF)-beta0.4248Inherited
Integrin domains0.4672Inherited
Tetratricopeptide repeat (TPR)0.5442Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Families 57/38 glycoside transferase middle domain0.000009091Direct
Glycoside hydrolase/deacetylase0.00004429Direct
Galactose mutarotase-like0.0001285Direct
HCP-like0.002173Inherited
L30e-like0.003677Inherited
Bcl-2 inhibitors of programmed cell death0.005678Inherited
Nuclear receptor ligand-binding domain0.04485Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.09444Inherited
Sema domain0.09925Inherited
TNF receptor-like0.09925Inherited
Leucine zipper domain0.1185Inherited
Plexin repeat0.1797Inherited
(Trans)glycosidases0.1911Inherited
C-type lectin-like0.1938Inherited
Riboflavin synthase domain-like0.2157Inherited
Flavoproteins0.2157Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.2157Inherited
EGF/Laminin0.4054Inherited
Integrin domains0.4341Inherited
Cystine-knot cytokines0.5133Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
88713,88688
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 0.000009091Direct
    48452,81901
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 0.0001235Direct
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.0001285Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.001126Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.01486Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.06397Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.06676Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.09925Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.2157Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.2433Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.6214Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.6599Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.00004429Direct
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.05587Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.7918Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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