SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Mammalian Phenotype (MP): abnormal cochlear outer hair cell morphology

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + + + 9:   mammalian phenotype [MP:0000001] <29>
+ + + + + + + 7:   nervous system phenotype [MP:0003631] <2>(98|128) (113|79|50)
+ + + + + + 6:   abnormal nervous system morphology [MP:0003632] <17>(76|104) (91|64|47)
+ + + + + 5:   abnormal somatic nervous system morphology [MP:0002752] <7>(34|47) (37|25|14)
+ + + + + 5:   abnormal membranous labyrinth morphology [MP:0000035] <2>(11|14) (12|9|5)
+ + + + + 5:   hearing/vestibular/ear phenotype [MP:0005377] <2>(20|24) (23|14|5)
+ + + + 4:   abnormal ear morphology [MP:0002102] <4>(16|21) (18|14|5)
+ + + + 4:   abnormal cochlear labyrinth morphology [MP:0004426] <1>(10|12) (11|8|5)
+ + + + 4:   abnormal somatic sensory system morphology [MP:0000959] <4>(26|38) (29|19|12)
+ + + 3:   abnormal inner ear morphology [MP:0000026] <15>(13|15) (13|11|5)
+ + + 3:   abnormal mechanoreceptor morphology [MP:0000972] <4>(10|12) (10|7|5)
+ + + 3:   abnormal cochlea morphology [MP:0000031] <15>(12|14) (13|8|5)
+ + + 3:   abnormal scala media morphology [MP:0003169] <9>(10|12) (11|8|5)
+ + 2:   abnormal hair cell morphology [MP:0000045] <3>(10|12) (10|7|5)
+ + 2:   abnormal organ of Corti morphology [MP:0000042] <7>(10|12) (10|7|5)
+ + 2:   abnormal cochlear sensory epithelium morphology [MP:0003308] <1>(10|12) (10|7|5)
+ 1:   abnormal cochlear hair cell morphology [MP:0002622] <6>(10|12) (10|7|5)
0:   abnormal cochlear outer hair cell morphology [MP:0004399] <6>(5|10) (6|7|5)
- 1:   abnormal outer hair cell stereociliary bundle morphology [MP:0004527] <6>(1|2) (2|2|1)
- 1:   abnormal cochlear outer hair cell number [MP:0004400] <2>(0|0) (0|3|4)
- 1:   abnormal cochlear OHC afferent innervation pattern [MP:0004747](0|0) (0|0|0)
- 1:   abnormal cochlear OHC efferent innervation pattern [MP:0004632](2|2) (2|1|0)
- 1:   cochlear outer hair cell degeneration [MP:0004404](1|1) (1|1|0)
- 1:   short cochlear outer hair cells [MP:0004466](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Frizzled cysteine-rich domain0.00001588Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0004929Direct
Nicotinic receptor ligand binding domain-like0.0004929Direct
Cadherin-like0.0007272Direct
lambda repressor-like DNA-binding domains0.006139Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Frizzled cysteine-rich domain0.000009755Direct
DIX domain0.00002124Direct
DEP domain0.0002925Direct
Growth factor receptor domain0.0003028Direct
Nicotinic receptor ligand binding domain-like0.0003297Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0003297Direct
Cadherin0.0003791Direct
PDZ domain0.0003925Direct
POU-specific domain0.001415Inherited
Motor proteins0.01114Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Frizzled cysteine-rich domain0.00000706Direct
Nicotinic receptor ligand binding domain-like0.0002598Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0002598Direct
Cadherin-like0.0003899Direct
lambda repressor-like DNA-binding domains0.003721Inherited
Second domain of FERM0.01166Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0001355Direct
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.0002598Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.0002598Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.0008641Direct
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.002059Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.003721Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.4024Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.000193Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0002414Direct
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0004559Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0004559Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.4686Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)