SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Mammalian Phenotype (MP): abnormal cochlear labyrinth morphology

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   hearing/vestibular/ear phenotype [MP:0005377] <2>(20|24) (23|14|5)
+ + + 3:   abnormal ear morphology [MP:0002102] <4>(16|21) (18|14|5)
+ + 2:   abnormal inner ear morphology [MP:0000026] <15>(13|15) (13|11|5)
+ 1:   abnormal membranous labyrinth morphology [MP:0000035] <2>(11|14) (12|9|5)
0:   abnormal cochlear labyrinth morphology [MP:0004426] <1>(10|12) (11|8|5)
- 1:   abnormal scala media morphology [MP:0003169] <9>(10|12) (11|8|5)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Frizzled cysteine-rich domain0.0001097Direct
Neurotransmitter-gated ion-channel transmembrane pore0.002633Inherited
Nicotinic receptor ligand binding domain-like0.002633Inherited
lambda repressor-like DNA-binding domains0.01749Inherited
PDZ domain-like0.02394Inherited
Second domain of FERM0.04709Inherited
EGF/Laminin0.36Inherited
Cadherin-like0.608Inherited
SH3-domain0.6626Inherited
Growth factor receptor domain0.7249Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Frizzled cysteine-rich domain0.00005552Direct
DIX domain0.00006916Direct
DEP domain0.0008745Direct
Nicotinic receptor ligand binding domain-like0.001539Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.001539Inherited
Growth factor receptor domain0.001738Inherited
PDZ domain0.002638Inherited
POU-specific domain0.004016Inherited
Motor proteins0.0326Inherited
EGF-type module0.4673Inherited
Cadherin0.5215Inherited
SH3-domain0.582Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Frizzled cysteine-rich domain0.00005344Direct
Neurotransmitter-gated ion-channel transmembrane pore0.001516Inherited
Nicotinic receptor ligand binding domain-like0.001516Inherited
lambda repressor-like DNA-binding domains0.0114Inherited
PDZ domain-like0.01594Inherited
Second domain of FERM0.03316Inherited
EGF/Laminin0.3143Inherited
Cadherin-like0.5627Inherited
SH3-domain0.6201Inherited
Growth factor receptor domain0.6854Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.7245Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.001516Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001771Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.00369Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.006569Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.5627Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.5627Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.6201Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.6835Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0006286Direct
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001557Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.001557Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.5627Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.6835Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)