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Mammalian Phenotype (MP): abnormal immune tolerance

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ 1:   abnormal immune system physiology [MP:0001790] <16>(59|84) (66|49|28)
0:   abnormal immune tolerance [MP:0005000] <3>(11|19) (13|8|1)
- 1:   abnormal clonal deletion [MP:0005001] <2>(0|0) (0|0|0)
- 1:   abnormal lymphocyte anergy [MP:0005004] <2>(0|0) (0|0|0)
- 1:   abnormal self tolerance [MP:0005005] <1>(11|19) (13|8|1)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Anaphylotoxins (complement system)0Direct
4-helical cytokines0.0002811Direct
TNF-like0.001619Inherited
Immunoglobulin0.001796Inherited
Fibronectin type III0.002743Inherited
L30e-like0.004355Inherited
TNF receptor-like0.01352Inherited
SH2 domain0.02616Inherited
DEATH domain0.03366Inherited
Toll/Interleukin receptor TIR domain0.1273Inherited
MHC antigen-recognition domain0.1404Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Anaphylotoxins (complement system)0Direct
Netrin-like domain (NTR/C345C module)0.0004226Direct
V set domains (antibody variable domain-like)0.000874Direct
TNF-like0.001257Inherited
PLC-like (P variant)0.001883Inherited
Interleukin 17F, IL-17F0.002231Inherited
Fibronectin type III0.002445Inherited
Long-chain cytokines0.00245Inherited
DEATH domain, DD0.01086Inherited
Short-chain cytokines0.01552Inherited
TNF receptor-like0.01623Inherited
SH2 domain0.0241Inherited
Interleukin-1 (IL-1)0.02494Inherited
Papain-like0.05026Inherited
C2 set domains0.05026Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.05473Inherited
C1 set domains (antibody constant domain-like)0.06674Inherited
Toll/Interleukin receptor TIR domain0.09411Inherited
MHC antigen-recognition domain0.1247Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Anaphylotoxins (complement system)0Direct
4-helical cytokines0.0001442Direct
TNF-like0.0009109Direct
Immunoglobulin0.001017Inherited
Fibronectin type III0.001582Inherited
L30e-like0.00258Inherited
TNF receptor-like0.00862Inherited
SH2 domain0.01755Inherited
DEATH domain0.02309Inherited
Toll/Interleukin receptor TIR domain0.09879Inherited
Protein kinase-like (PK-like)0.1094Inherited
MHC antigen-recognition domain0.1102Inherited
p53-like transcription factors0.1636Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49410,50242
  • 49410 - Alpha-macroglobulin receptor domain
  • 50242 - TIMP-like
  • 0Direct
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.0004626Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.02043Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.03147Inherited
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.04467Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.04628Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.04628Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.04803Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.001853Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)