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Mammalian Phenotype (MP): abnormal immune tolerance

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ 1:   abnormal immune system physiology [MP:0001790] <16>(59|84) (66|49|28)
0:   abnormal immune tolerance [MP:0005000] <3>(11|19) (13|8|1)
- 1:   abnormal clonal deletion [MP:0005001] <2>(0|0) (0|0|0)
- 1:   abnormal lymphocyte anergy [MP:0005004] <2>(0|0) (0|0|0)
- 1:   abnormal self tolerance [MP:0005005] <1>(11|19) (13|8|1)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Anaphylotoxins (complement system)0Direct
4-helical cytokines0.0002828Direct
Immunoglobulin0.001567Inherited
TNF-like0.001625Inherited
Fibronectin type III0.00276Inherited
L30e-like0.004357Inherited
TNF receptor-like0.01355Inherited
SH2 domain0.02629Inherited
DEATH domain0.03377Inherited
Toll/Interleukin receptor TIR domain0.1274Inherited
MHC antigen-recognition domain0.1406Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Anaphylotoxins (complement system)0Direct
Netrin-like domain (NTR/C345C module)0.0004226Direct
V set domains (antibody variable domain-like)0.0008786Direct
TNF-like0.001262Inherited
PLC-like (P variant)0.001889Inherited
Interleukin 17F, IL-17F0.002235Inherited
Long-chain cytokines0.002455Inherited
Fibronectin type III0.002461Inherited
DEATH domain, DD0.01089Inherited
Short-chain cytokines0.01554Inherited
TNF receptor-like0.01627Inherited
SH2 domain0.0242Inherited
Interleukin-1 (IL-1)0.02499Inherited
C2 set domains0.05034Inherited
Papain-like0.05034Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.05481Inherited
C1 set domains (antibody constant domain-like)0.06686Inherited
Toll/Interleukin receptor TIR domain0.09433Inherited
MHC antigen-recognition domain0.1249Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Anaphylotoxins (complement system)0Direct
4-helical cytokines0.0001451Direct
Immunoglobulin0.0008794Direct
TNF-like0.0009141Direct
Fibronectin type III0.001592Inherited
L30e-like0.00258Inherited
TNF receptor-like0.008644Inherited
SH2 domain0.01763Inherited
DEATH domain0.02316Inherited
Toll/Interleukin receptor TIR domain0.09894Inherited
Protein kinase-like (PK-like)0.1099Inherited
MHC antigen-recognition domain0.1104Inherited
p53-like transcription factors0.1638Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49410,50242
  • 49410 - Alpha-macroglobulin receptor domain
  • 50242 - TIMP-like
  • 0Direct
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.0004637Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.0205Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.03157Inherited
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.04471Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.04635Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.04635Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.04807Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.001857Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)