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Mammalian Phenotype (MP): increased lymphocyte cell number

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   mammalian phenotype [MP:0000001] <29>
+ + + + + + 6:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + + + 6:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + + 5:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(57|86) (66|47|21)
+ + + + + 5:   abnormal immune system morphology [MP:0000685] <3>(50|76) (60|35|18)
+ + + + 4:   abnormal hematopoietic cell morphology [MP:0013656] <9>(48|77) (60|43|18)
+ + + + 4:   abnormal immune system cell morphology [MP:0000716] <5>(37|63) (48|29|16)
+ + + 3:   abnormal leukocyte morphology [MP:0008246] <4>(36|62) (47|29|15)
+ + + 3:   abnormal hematopoietic cell number [MP:0011180] <7>(34|57) (43|29|13)
+ + + 3:   abnormal mononuclear cell morphology [MP:0008247] <2>(33|57) (41|28|14)
+ + 2:   abnormal lymphocyte morphology [MP:0002619] <5>(27|46) (33|26|14)
+ + 2:   abnormal leukocyte cell number [MP:0000217] <8>(29|49) (37|25|12)
+ + 2:   increased hematopoietic cell number [MP:0011181] <4>(12|26) (19|11|7)
+ 1:   increased leukocyte cell number [MP:0000218] <5>(9|23) (15|11|7)
+ 1:   abnormal lymphocyte cell number [MP:0000717] <6>(18|38) (25|21|9)
0:   increased lymphocyte cell number [MP:0005013] <4>(3|12) (8|6|6)
- 1:   increased T cell number [MP:0005015] <11>(0|2) (2|1|1)
- 1:   increased NK cell number [MP:0008044] <5>(0|0) (0|0|0)
- 1:   increased B cell number [MP:0005014] <3>(3|8) (5|3|2)
- 1:   increased large unstained cell number [MP:0012362](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Toll/Interleukin receptor TIR domain0.3175Inherited
DBL homology domain (DH-domain)0.5407Inherited
Calponin-homology domain, CH-domain0.6433Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Interferon regulatory factor0.0003625Direct
SH2 domain0.0008413Direct
Nuclear receptor coactivator interlocking domain0.002263Inherited
TNF receptor-like0.009305Inherited
Interferon regulatory factor 3 (IRF3), transactivation domain0.009516Inherited
Higher-molecular-weight phosphotyrosine protein phosphatases0.03057Inherited
DEATH domain, DD0.03901Inherited
Bcl-2 inhibitors of programmed cell death0.08496Inherited
CCCH zinc finger0.1401Inherited
Toll/Interleukin receptor TIR domain0.1799Inherited
DBL homology domain (DH-domain)0.5094Inherited
Calponin-homology domain, CH-domain0.6128Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SH2 domain0.0006735Direct
Nuclear receptor coactivator interlocking domain0.001928Inherited
TNF receptor-like0.009548Inherited
Bcl-2 inhibitors of programmed cell death0.08002Inherited
CCCH zinc finger0.1339Inherited
Toll/Interleukin receptor TIR domain0.2734Inherited
DBL homology domain (DH-domain)0.4938Inherited
Calponin-homology domain, CH-domain0.5995Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0Direct
    47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.00001654Direct
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.0002869Direct
    53300,69318
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 0.1339Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.4938Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50729,50044,55550
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0Direct
    50044,55550,50044
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0Direct
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.0005415Direct
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0005415Direct
    53300,69318,69179
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.1339Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)