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Mammalian Phenotype (MP): decreased double-positive T cell number

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + + + + 10:   mammalian phenotype [MP:0000001] <29>
+ + + + + + + + 8:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + + + + 7:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(57|86) (66|47|21)
+ + + + + + + 7:   abnormal blood cell morphology/development [MP:0002429] <3>(26|35) (28|24|9)
+ + + + + + + 7:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + + + + 7:   abnormal blood cell morphology [MP:0013657] <4>(31|49) (37|35|14)
+ + + + + + 6:   abnormal immune system morphology [MP:0000685] <3>(50|76) (60|35|18)
+ + + + + + 6:   abnormal hemopoiesis [MP:0013693] <2>(25|34) (27|24|9)
+ + + + + + 6:   abnormal hematopoietic cell morphology [MP:0013656] <9>(48|77) (60|43|18)
+ + + + + 5:   abnormal immune system cell morphology [MP:0000716] <5>(37|63) (48|29|16)
+ + + + + 5:   abnormal leukocyte morphology [MP:0008246] <4>(36|62) (47|29|15)
+ + + + + 5:   abnormal definitive hematopoiesis [MP:0002123] <4>(24|34) (26|24|9)
+ + + + + 5:   abnormal mononuclear cell morphology [MP:0008247] <2>(33|57) (41|28|14)
+ + + + + 5:   abnormal hematopoietic cell number [MP:0011180] <7>(34|57) (43|29|13)
+ + + + 4:   abnormal leukopoiesis [MP:0005460] <3>(17|28) (21|18|8)
+ + + + 4:   abnormal leukocyte cell number [MP:0000217] <8>(29|49) (37|25|12)
+ + + + 4:   abnormal lymphocyte morphology [MP:0002619] <5>(27|46) (33|26|14)
+ + + + 4:   decreased hematopoietic cell number [MP:0011182] <5>(21|34) (27|21|11)
+ + + 3:   abnormal T cell morphology [MP:0008037] <9>(14|25) (18|19|11)
+ + + 3:   abnormal lymphopoiesis [MP:0002401] <3>(17|25) (21|15|6)
+ + + 3:   decreased leukocyte cell number [MP:0000221] <5>(17|28) (24|18|10)
+ + + 3:   abnormal lymphocyte cell number [MP:0000717] <6>(18|38) (25|21|9)
+ + 2:   abnormal T cell number [MP:0006387] <11>(8|22) (16|15|7)
+ + 2:   abnormal alpha-beta T cell morphology [MP:0012762] <13>(7|17) (8|14|6)
+ + 2:   abnormal T cell differentiation [MP:0002145] <9>(6|9) (10|8|3)
+ + 2:   decreased lymphocyte cell number [MP:0005016] <5>(16|28) (22|16|7)
+ 1:   abnormal double-positive T cell morphology [MP:0002408] <2>(1|2) (1|3|1)
+ 1:   decreased T cell number [MP:0005018] <12>(8|15) (13|11|5)
0:   decreased double-positive T cell number [MP:0005092](1|2) (1|2|1)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
E2F-DP heterodimerization region0.0002818Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
E2F dimerization segment0.00008612Direct
Cell cycle transcription factor e2f-dp0.0005016Direct


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
E2F-DP heterodimerization region0.0001445Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.0001445Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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