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Mammalian Phenotype (MP): decreased cardiac muscle contractility

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   muscle phenotype [MP:0005369] <2>(49|57) (54|37|28)
+ + + 3:   abnormal muscle physiology [MP:0002106] <23>(25|33) (27|16|11)
+ + + 3:   cardiovascular system phenotype [MP:0005385] <2>(67|85) (77|57|35)
+ + 2:   abnormal cardiovascular system physiology [MP:0001544] <24>(39|45) (46|26|17)
+ + 2:   abnormal muscle contractility [MP:0005620] <3>(12|15) (13|10|7)
+ 1:   abnormal cardiac muscle contractility [MP:0002972] <2>(6|8) (7|3|3)
+ 1:   impaired muscle contractility [MP:0000738] <3>(12|14) (13|10|7)
0:   decreased cardiac muscle contractility [MP:0005140] <1>(6|8) (7|3|3)
- 1:   decreased ventricle muscle contractility [MP:0005598](0|0) (1|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
SRF-like0.00002491Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0001971Direct
Riboflavin synthase domain-like0.0001971Direct
Inhibitor of apoptosis (IAP) repeat0.0004753Direct
Flavoproteins0.0004753Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
L domain0.000009379Direct
Cytochrome p450 reductase N-terminal domain-like0.00001516Direct
SRF-like0.00001516Direct
NADPH-cytochrome p450 reductase-like0.00006173Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.00006173Direct
Inhibitor of apoptosis (IAP) repeat0.0001559Direct
LIM domain0.0006804Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
SRF-like0.00001135Direct
Riboflavin synthase domain-like0.00009952Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.00009952Direct
Inhibitor of apoptosis (IAP) repeat0.0002501Direct
Flavoproteins0.0002501Direct
dsRNA-binding domain-like0.006645Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.000006645Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.000006645Direct
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.00004758Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.000006645Direct
    57924,57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.00004758Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0002971Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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