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Mammalian Phenotype (MP): abnormal pancreatic islet morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   endocrine/exocrine gland phenotype [MP:0005379] <2>(51|81) (55|36|12)
+ + + 3:   abnormal gland morphology [MP:0002163] <8>(44|71) (50|31|11)
+ + 2:   abnormal pancreas morphology [MP:0001944] <17>(7|12) (8|7|4)
+ + 2:   abnormal endocrine gland morphology [MP:0013560] <7>(16|29) (21|19|4)
+ 1:   abnormal endocrine pancreas morphology [MP:0009165] <1>(4|8) (5|7|2)
0:   abnormal pancreatic islet morphology [MP:0005215] <9>(4|8) (5|7|2)
- 1:   abnormal pancreatic beta cell morphology [MP:0005217] <5>(1|5) (2|3|0)
- 1:   abnormal PP cell morphology [MP:0009184] <3>(0|0) (0|0|0)
- 1:   abnormal pancreatic alpha cell morphology [MP:0005216] <3>(0|0) (0|0|0)
- 1:   abnormal pancreatic delta cell morphology [MP:0005218] <3>(1|1) (1|0|0)
- 1:   abnormal pancreatic epsilon cell morphology [MP:0009189] <3>(0|0) (0|0|0)
- 1:   abnormal pancreatic islet number [MP:0009166] <2>(0|0) (0|0|0)
- 1:   abnormal pancreatic islet size [MP:0009170] <2>(1|2) (1|2|0)
- 1:   absent pancreatic islets [MP:0009173](0|0) (0|0|0)
- 1:   disorganized pancreatic islets [MP:0009254](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
STAT0.0004463Direct
Transcription factor STAT-4 N-domain0.0004463Direct
Insulin-like0.001205Inherited
Homeodomain-like0.9795Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
STAT DNA-binding domain0.0002928Direct
STAT0.0002928Direct
Transcription factor STAT-4 N-domain0.0002928Direct
Forkhead DNA-binding domain0.0007168Direct
Insulin-like0.0008177Direct
Paired domain0.0008177Direct
Phosphotyrosine-binding domain (PTB)0.00498Inherited
Homeodomain0.968Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
STAT0.0002347Direct
Transcription factor STAT-4 N-domain0.0002347Direct
Insulin-like0.0006642Direct
"Winged helix" DNA-binding domain0.07466Inherited
Homeodomain-like0.9622Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57184,57610
  • 57184 - Growth factor receptor domain
  • 57610 - Thyroglobulin type-1 domain
  • 0.0001155Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0002347Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.0002347Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0002347Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.008382Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.01576Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.1042Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0002347Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0002347Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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