SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Mammalian Phenotype (MP): abnormal retinal ganglion layer morphology

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + + 8:   mammalian phenotype [MP:0000001] <29>
+ + + + + + + 7:   vision/eye phenotype [MP:0005391] <2>(43|53) (50|27|17)
+ + + + + + 6:   abnormal eye morphology [MP:0002092] <23>(39|49) (46|25|15)
+ + + + + 5:   abnormal posterior eye segment morphology [MP:0005195] <4>(21|24) (23|14|8)
+ + + + 4:   abnormal ocular fundus morphology [MP:0002864] <2>(19|23) (21|14|8)
+ + + 3:   abnormal retina morphology [MP:0001325] <23>(19|23) (21|14|8)
+ + 2:   abnormal retinal layer morphology [MP:0003727] <3>(11|16) (12|8|6)
+ 1:   abnormal retinal neuronal layer morphology [MP:0006069] <7>(11|15) (11|8|5)
0:   abnormal retinal ganglion layer morphology [MP:0005241] <5>(2|5) (3|2|1)
- 1:   abnormal retinal ganglion cell morphology [MP:0008056] <3>(2|5) (3|2|0)
- 1:   absent retinal ganglion layer [MP:0008510](0|0) (0|0|0)
- 1:   disorganized retinal ganglion layer [MP:0008509](0|0) (0|0|0)
- 1:   thick retinal ganglion layer [MP:0008508](0|0) (0|0|0)
- 1:   thin retinal ganglion layer [MP:0008507](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
E2F-DP heterodimerization region0.00005559Direct
Cyclin-like0.0007272Direct


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Retinoblastoma tumor suppressor domains0Direct
E2F dimerization segment0.00001561Direct
Cell cycle transcription factor e2f-dp0.00009824Direct
Extracellular domain of cell surface receptors0.0001511Direct
POU-specific domain0.001073Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
E2F-DP heterodimerization region0.00002613Direct
Cyclin-like0.0003898Direct
HLH, helix-loop-helix DNA-binding domain0.1097Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.00002613Direct
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.001566Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0000479Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)