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Mammalian Phenotype (MP): abnormal eye physiology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   mammalian phenotype [MP:0000001] <29>
+ 1:   vision/eye phenotype [MP:0005391] <2>(43|53) (50|27|17)
0:   abnormal eye physiology [MP:0005253] <25>(8|9) (9|5|2)
- 1:   eye inflammation [MP:0001851] <12>(0|0) (0|0|0)
- 1:   abnormal vision [MP:0002090] <8>(0|0) (0|0|0)
- 1:   abnormal eye movement [MP:0001389] <7>(0|0) (0|0|0)
- 1:   abnormal electroretinogram waveform feature [MP:0012029] <5>(0|0) (0|0|0)
- 1:   abnormal tear production [MP:0020218] <5>(0|0) (0|0|0)
- 1:   abnormal eye electrophysiology [MP:0005551] <3>(4|4) (4|4|2)
- 1:   abnormal intraocular pressure [MP:0005257] <2>(0|0) (0|0|0)
- 1:   abnormal lacrimal apparatus physiology [MP:0013450] <2>(0|0) (0|0|0)
- 1:   altered response to retinal ischemic injury [MP:0012048] <2>(0|0) (0|0|0)
- 1:   eye hemorrhage [MP:0006203] <2>(0|0) (0|0|0)
- 1:   abnormal lens epithelium apoptosis [MP:0008793] <1>(0|0) (0|0|0)
- 1:   abnormal lens fiber apoptosis [MP:0008795] <1>(0|0) (0|0|0)
- 1:   abnormal pupillary reflex [MP:0002638] <1>(2|2) (2|1|0)
- 1:   photosensitivity [MP:0001999] <1>(0|0) (0|0|0)
- 1:   abnormal blood-retinal barrier function [MP:0014179](0|0) (0|0|0)
- 1:   abnormal retinal apoptosis [MP:0006072](1|2) (2|0|0)
- 1:   abnormal tear film physiology [MP:0014132](0|0) (0|0|0)
- 1:   delayed dark adaptation [MP:0003011](1|1) (1|0|0)
- 1:   dry eyes [MP:0001337](0|0) (0|0|0)
- 1:   eye discharge [MP:0013145](0|0) (0|0|0)
- 1:   eyelid apraxia [MP:0006251](0|0) (0|0|0)
- 1:   increased corneal light-scattering [MP:0003096](0|0) (0|0|0)
- 1:   involuntary contraction of eyelids [MP:0006244](0|0) (0|0|0)
- 1:   lagophthalmos [MP:0006248](0|0) (0|0|0)
- 1:   retinal ischemia [MP:0006190](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Transducin (heterotrimeric G protein), gamma chain0.001624Inherited
GAF domain-like0.001953Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.02141Inherited
Nicotinic receptor ligand binding domain-like0.02141Inherited
Transducin (alpha subunit), insertion domain0.04134Inherited
Regulator of G-protein signaling, RGS0.07912Inherited
Cyclin-like0.1301Inherited
NAD(P)-binding Rossmann-fold domains0.4574Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Retinoblastoma tumor suppressor domains0Direct
GAF domain0.001386Inherited
Transducin (heterotrimeric G protein), gamma chain0.006853Inherited
Nicotinic receptor ligand binding domain-like0.01835Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.01835Inherited
Transducin (alpha subunit), insertion domain0.03403Inherited
Regulator of G-protein signaling, RGS0.06972Inherited
Tyrosine-dependent oxidoreductases0.1629Inherited
HLH, helix-loop-helix DNA-binding domain0.4021Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Transducin (heterotrimeric G protein), gamma chain0.0009136Direct
GAF domain-like0.001109Inherited
Nicotinic receptor ligand binding domain-like0.01412Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.01412Inherited
Transducin (alpha subunit), insertion domain0.02877Inherited
Regulator of G-protein signaling, RGS0.05835Inherited
Cyclin-like0.1013Inherited
HLH, helix-loop-helix DNA-binding domain0.3631Inherited
NAD(P)-binding Rossmann-fold domains0.4096Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48670,48097
  • 48670 - Transducin (heterotrimeric G protein), gamma chain
  • 48097 - Regulator of G-protein signaling, RGS
  • 0.0001215Direct
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.001109Inherited
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.001109Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.01412Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.02362Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.001109Inherited
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.039Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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