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Mammalian Phenotype (MP): renal/urinary system phenotype

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   mammalian phenotype [MP:0000001] <29>
0:   renal/urinary system phenotype [MP:0005367] <2>(41|47) (46|26|11)
- 1:   abnormal renal/urinary system morphology [MP:0000516] <14>(31|36) (36|22|11)
- 1:   abnormal renal/urinary system physiology [MP:0005502] <6>(20|21) (25|10|1)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Anaphylotoxins (complement system)0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Growth factor receptor domain0.000002793Direct
Aquaporin-like0.00006027Direct
EGF/Laminin0.0001464Direct
(Trans)glycosidases0.0003233Direct
Families 57/38 glycoside transferase middle domain0.0007994Direct
Notch domain0.0007994Direct
MFS general substrate transporter0.000812Direct
Phoshotransferase/anion transport protein0.001055Inherited
CBS-domain pair0.00113Inherited
Clc chloride channel0.001838Inherited
Riboflavin synthase domain-like0.00212Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.00212Inherited
Cystine-knot cytokines0.002367Inherited
Glycoside hydrolase/deacetylase0.002968Inherited
L-aspartase-like0.003916Inherited
Galactose mutarotase-like0.007043Inherited
Flavoproteins0.007043Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.007133Inherited
FnI-like domain0.007815Inherited
CalX-like0.01347Inherited
Plexin repeat0.01603Inherited
Nuclear receptor ligand-binding domain0.03618Inherited
Toll/Interleukin receptor TIR domain0.03901Inherited
HCP-like0.04142Inherited
Sema domain0.04966Inherited
TNF receptor-like0.05388Inherited
C-type lectin-like0.05438Inherited
Integrin domains0.05725Inherited
L30e-like0.06225Inherited
Bcl-2 inhibitors of programmed cell death0.08608Inherited
Integrin alpha N-terminal domain0.09247Inherited
TPR-like0.1695Inherited
Cyclin-like0.2567Inherited
ARM repeat0.2605Inherited
Cadherin-like0.4144Inherited
Metalloproteases ("zincins"), catalytic domain0.4463Inherited
Homeodomain-like0.582Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.6717Inherited
Nicotinic receptor ligand binding domain-like0.6717Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Anaphylotoxins (complement system)0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Retinoblastoma tumor suppressor domains0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Growth factor receptor domain0.000006058Direct
Aquaporin-like0.00003718Direct
Arylsulfatase0.0002829Direct
CBS-domain pair0.0003815Direct
Notch domain0.000505Direct
NADPH-cytochrome p450 reductase-like0.000505Direct
alpha-mannosidase0.000505Direct
alpha-mannosidase, domain 20.000505Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.000505Direct
VWC domain0.0007545Direct
Clc chloride channel0.001229Inherited
Noncollagenous (NC1) domain of collagen IV0.001995Inherited
alpha-mannosidase, C-terminal domain0.00263Inherited
Anion transport protein, cytoplasmic domain0.002724Inherited
EGF-type module0.002849Inherited
Transforming growth factor (TGF)-beta0.00475Inherited
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.004979Inherited
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.004979Inherited
CalX-beta domain0.00983Inherited
Platelet-derived growth factor-like0.00983Inherited
Plexin repeat0.01265Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain0.01981Inherited
Nuclear receptor0.02207Inherited
Toll/Interleukin receptor TIR domain0.02473Inherited
Laminin-type module0.0267Inherited
Nuclear receptor ligand-binding domain0.02969Inherited
Sema domain0.0405Inherited
Tetratricopeptide repeat (TPR)0.04628Inherited
Integrin domains0.04686Inherited
TNF receptor-like0.04809Inherited
PLC-like (P variant)0.04836Inherited
Forkhead DNA-binding domain0.05591Inherited
Rhodopsin-like0.06765Inherited
Bcl-2 inhibitors of programmed cell death0.0701Inherited
Integrin alpha N-terminal domain0.1076Inherited
Short-chain cytokines0.1775Inherited
Fibroblast growth factors (FGF)0.2807Inherited
Cadherin0.3479Inherited
Leucine zipper domain0.4635Inherited
I set domains0.4917Inherited
Nicotinic receptor ligand binding domain-like0.6528Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.6528Inherited
Homeodomain0.7561Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Anaphylotoxins (complement system)0Direct
Growth factor receptor domain0.000001174Direct
Aquaporin-like0.00002851Direct
EGF/Laminin0.000073Direct
(Trans)glycosidases0.0001675Direct
Notch domain0.0004317Direct
Families 57/38 glycoside transferase middle domain0.0004317Direct
MFS general substrate transporter0.0004388Direct
Phoshotransferase/anion transport protein0.0005783Direct
CBS-domain pair0.0006213Direct
Clc chloride channel0.00104Inherited
Riboflavin synthase domain-like0.001208Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.001208Inherited
Cystine-knot cytokines0.001355Inherited
Glycoside hydrolase/deacetylase0.001721Inherited
L-aspartase-like0.002304Inherited
Flavoproteins0.004312Inherited
Galactose mutarotase-like0.004312Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.004373Inherited
FnI-like domain0.004798Inherited
CalX-like0.008588Inherited
Plexin repeat0.01035Inherited
Acyl-CoA dehydrogenase NM domain-like0.01469Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.01469Inherited
Nuclear receptor ligand-binding domain0.02491Inherited
Toll/Interleukin receptor TIR domain0.02701Inherited
HCP-like0.02885Inherited
Sema domain0.03506Inherited
TNF receptor-like0.0383Inherited
C-type lectin-like0.03869Inherited
Integrin domains0.041Inherited
L30e-like0.04498Inherited
Bcl-2 inhibitors of programmed cell death0.06403Inherited
Integrin alpha N-terminal domain0.06927Inherited
TPR-like0.1357Inherited
Family A G protein-coupled receptor-like0.151Inherited
Cyclin-like0.2159Inherited
ARM repeat0.2194Inherited
Cadherin-like0.3674Inherited
Metalloproteases ("zincins"), catalytic domain0.3987Inherited
Cytokine0.4005Inherited
Leucine zipper domain0.4349Inherited
Homeodomain-like0.5357Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.6295Inherited
Nicotinic receptor ligand binding domain-like0.6295Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49410,50242
  • 49410 - Alpha-macroglobulin receptor domain
  • 50242 - TIMP-like
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0001692Direct
    88713,88688
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 0.0004317Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.002304Inherited
    48452,81901
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 0.002304Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.003539Inherited
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.004312Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.004585Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.007605Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.009308Inherited
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.01469Inherited
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.01645Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.03506Inherited
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.06723Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.06723Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.07984Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.1158Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.137Inherited
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.1653Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.1653Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2259Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.2926Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.3871Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.4478Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.4559Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.6295Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.001721Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001815Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.003807Inherited
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.0429Inherited
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.04498Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.06654Inherited
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.06723Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.08174Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1653Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.3541Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.4081Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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