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Mammalian Phenotype (MP): renal/urinary system phenotype

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   mammalian phenotype [MP:0000001] <29>
0:   renal/urinary system phenotype [MP:0005367] <2>(41|47) (46|26|11)
- 1:   abnormal renal/urinary system morphology [MP:0000516] <14>(31|36) (36|22|11)
- 1:   abnormal renal/urinary system physiology [MP:0005502] <6>(20|21) (25|10|1)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Anaphylotoxins (complement system)0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Growth factor receptor domain0.000002741Direct
Aquaporin-like0.00005993Direct
EGF/Laminin0.0001438Direct
(Trans)glycosidases0.0003203Direct
Families 57/38 glycoside transferase middle domain0.0007971Direct
Notch domain0.0007971Direct
MFS general substrate transporter0.0008043Direct
Phoshotransferase/anion transport protein0.00105Inherited
CBS-domain pair0.001124Inherited
Clc chloride channel0.00183Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.002109Inherited
Riboflavin synthase domain-like0.002109Inherited
Cystine-knot cytokines0.002343Inherited
Glycoside hydrolase/deacetylase0.002958Inherited
L-aspartase-like0.003904Inherited
Galactose mutarotase-like0.007024Inherited
Flavoproteins0.007024Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.007055Inherited
FnI-like domain0.007767Inherited
CalX-like0.01343Inherited
Plexin repeat0.03115Inherited
Nuclear receptor ligand-binding domain0.03598Inherited
Toll/Interleukin receptor TIR domain0.03885Inherited
HCP-like0.04134Inherited
TNF receptor-like0.0537Inherited
C-type lectin-like0.05406Inherited
Integrin domains0.05702Inherited
L30e-like0.06211Inherited
Bcl-2 inhibitors of programmed cell death0.08595Inherited
Sema domain0.09152Inherited
Integrin alpha N-terminal domain0.09219Inherited
TPR-like0.1688Inherited
Cyclin-like0.2562Inherited
ARM repeat0.2593Inherited
Cadherin-like0.4135Inherited
Metalloproteases ("zincins"), catalytic domain0.4451Inherited
Homeodomain-like0.5803Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.671Inherited
Nicotinic receptor ligand binding domain-like0.671Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Retinoblastoma tumor suppressor domains0Direct
Anaphylotoxins (complement system)0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Growth factor receptor domain0.000005955Direct
Aquaporin-like0.00003692Direct
Arylsulfatase0.0002812Direct
CBS-domain pair0.0003791Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.0005026Direct
Notch domain0.0005026Direct
alpha-mannosidase, domain 20.0005026Direct
NADPH-cytochrome p450 reductase-like0.0005026Direct
alpha-mannosidase0.0005026Direct
VWC domain0.0007514Direct
Clc chloride channel0.001223Inherited
Noncollagenous (NC1) domain of collagen IV0.001986Inherited
alpha-mannosidase, C-terminal domain0.002619Inherited
Anion transport protein, cytoplasmic domain0.002711Inherited
EGF-type module0.002814Inherited
Transforming growth factor (TGF)-beta0.004714Inherited
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.004959Inherited
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.004959Inherited
CalX-beta domain0.009785Inherited
Platelet-derived growth factor-like0.009785Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain0.01974Inherited
Nuclear receptor0.02192Inherited
Toll/Interleukin receptor TIR domain0.02461Inherited
Plexin repeat0.02509Inherited
Laminin-type module0.02657Inherited
Nuclear receptor ligand-binding domain0.0295Inherited
Tetratricopeptide repeat (TPR)0.046Inherited
Integrin domains0.04666Inherited
TNF receptor-like0.0479Inherited
PLC-like (P variant)0.04811Inherited
Forkhead DNA-binding domain0.05561Inherited
Rhodopsin-like0.06684Inherited
Bcl-2 inhibitors of programmed cell death0.0699Inherited
Sema domain0.07718Inherited
Integrin alpha N-terminal domain0.1072Inherited
Short-chain cytokines0.1771Inherited
Fibroblast growth factors (FGF)0.28Inherited
Cadherin0.347Inherited
Leucine zipper domain0.4626Inherited
I set domains0.5792Inherited
Nicotinic receptor ligand binding domain-like0.652Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.652Inherited
Homeodomain0.7545Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Anaphylotoxins (complement system)0Direct
Growth factor receptor domain0.00000115Direct
Aquaporin-like0.00002831Direct
EGF/Laminin0.00007167Direct
(Trans)glycosidases0.0001658Direct
Families 57/38 glycoside transferase middle domain0.0004299Direct
Notch domain0.0004299Direct
MFS general substrate transporter0.0004338Direct
Phoshotransferase/anion transport protein0.0005751Direct
CBS-domain pair0.0006174Direct
Clc chloride channel0.001035Inherited
Riboflavin synthase domain-like0.001202Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.001202Inherited
Cystine-knot cytokines0.001341Inherited
Glycoside hydrolase/deacetylase0.001715Inherited
L-aspartase-like0.002296Inherited
Galactose mutarotase-like0.004297Inherited
Flavoproteins0.004297Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.004321Inherited
FnI-like domain0.004769Inherited
CalX-like0.008558Inherited
Acyl-CoA dehydrogenase NM domain-like0.01465Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.01465Inherited
Plexin repeat0.02126Inherited
Nuclear receptor ligand-binding domain0.02476Inherited
Toll/Interleukin receptor TIR domain0.02689Inherited
HCP-like0.02877Inherited
TNF receptor-like0.03815Inherited
C-type lectin-like0.03844Inherited
Integrin domains0.04082Inherited
L30e-like0.04485Inherited
Bcl-2 inhibitors of programmed cell death0.0639Inherited
Sema domain0.06852Inherited
Integrin alpha N-terminal domain0.06908Inherited
TPR-like0.135Inherited
Family A G protein-coupled receptor-like0.1498Inherited
Cyclin-like0.2155Inherited
ARM repeat0.2183Inherited
Cadherin-like0.3666Inherited
Metalloproteases ("zincins"), catalytic domain0.3975Inherited
Cytokine0.3998Inherited
Leucine zipper domain0.4341Inherited
Homeodomain-like0.5339Inherited
Nicotinic receptor ligand binding domain-like0.6287Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.6287Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49410,50242
  • 49410 - Alpha-macroglobulin receptor domain
  • 50242 - TIMP-like
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0001671Direct
    88713,88688
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 0.0004299Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.002296Inherited
    48452,81901
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 0.002296Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.003517Inherited
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.004297Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.004572Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.007557Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.009263Inherited
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.01465Inherited
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0164Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.06703Inherited
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.06703Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.06852Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.07958Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.1154Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.1366Inherited
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.1649Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.1649Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2252Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.2919Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.3867Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.4464Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.4552Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.6287Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.001715Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001801Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.003789Inherited
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.04276Inherited
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.04485Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.06617Inherited
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.06703Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.08146Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1649Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.3536Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.4073Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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