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Mammalian Phenotype (MP): hearing/vestibular/ear phenotype

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   mammalian phenotype [MP:0000001] <29>
0:   hearing/vestibular/ear phenotype [MP:0005377] <2>(20|24) (23|14|5)
- 1:   abnormal ear physiology [MP:0003878] <9>(8|8) (8|3|0)
- 1:   abnormal ear morphology [MP:0002102] <4>(16|21) (18|14|5)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Homeodomain-like0.0000003113Direct
Nuclear receptor ligand-binding domain0.0000581Direct
Glucocorticoid receptor-like (DNA-binding domain)0.0005048Direct
Growth factor receptor domain0.001301Inherited
Serine protease inhibitors0.002111Inherited
EGF/Laminin0.004001Inherited
Frizzled cysteine-rich domain0.004806Inherited
Phoshotransferase/anion transport protein0.00608Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.013Inherited
Nicotinic receptor ligand binding domain-like0.013Inherited
lambda repressor-like DNA-binding domains0.04734Inherited
Cytokine0.07072Inherited
Second domain of FERM0.07343Inherited
Cadherin-like0.1066Inherited
Cystine-knot cytokines0.135Inherited
SH3-domain0.1956Inherited
(Trans)glycosidases0.2197Inherited
DEATH domain0.2697Inherited
Voltage-gated potassium channels0.2935Inherited
PDZ domain-like0.3614Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Retinoblastoma tumor suppressor domains0Direct
Homeodomain0.0000004414Direct
Nuclear receptor0.00002141Direct
Nuclear receptor ligand-binding domain0.00003718Direct
Paired domain0.0002339Direct
DIX domain0.0002408Direct
Clathrin adaptor core protein0.0004789Direct
Forkhead DNA-binding domain0.002976Inherited
Frizzled cysteine-rich domain0.003338Inherited
Phosphotyrosine-binding domain (PTB)0.004353Inherited
Growth factor receptor domain0.004632Inherited
Motor proteins0.006143Inherited
POU-specific domain0.008756Inherited
Nicotinic receptor ligand binding domain-like0.009679Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.009679Inherited
Fibroblast growth factors (FGF)0.02634Inherited
DEP domain0.03295Inherited
Transforming growth factor (TGF)-beta0.07388Inherited
Cadherin0.07388Inherited
Transducin (alpha subunit), insertion domain0.07799Inherited
EGF-type module0.106Inherited
SH3-domain0.1797Inherited
Voltage-gated potassium channels0.2236Inherited
PDZ domain0.2429Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Homeodomain-like0.0000001252Direct
Nuclear receptor ligand-binding domain0.00002741Direct
Glucocorticoid receptor-like (DNA-binding domain)0.0002672Direct
FnI-like domain0.0007029Direct
Growth factor receptor domain0.0007224Direct
Serine protease inhibitors0.001203Inherited
EGF/Laminin0.00236Inherited
Frizzled cysteine-rich domain0.00287Inherited
Phoshotransferase/anion transport protein0.003681Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.008265Inherited
Nicotinic receptor ligand binding domain-like0.008265Inherited
lambda repressor-like DNA-binding domains0.03335Inherited
Cytokine0.05173Inherited
Second domain of FERM0.0539Inherited
Transducin (alpha subunit), insertion domain0.07216Inherited
Cadherin-like0.08111Inherited
Cystine-knot cytokines0.1056Inherited
SH3-domain0.1593Inherited
(Trans)glycosidases0.1814Inherited
DEATH domain0.2282Inherited
Voltage-gated potassium channels0.2507Inherited
PDZ domain-like0.3157Inherited
GTPase activation domain, GAP0.6215Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.0000005192Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0005139Direct
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0005143Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0006749Direct
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.006529Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.008265Inherited
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.0152Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.01583Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.06022Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.06025Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.07132Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.1538Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.1538Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.2185Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0001222Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0007436Direct
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001958Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.001958Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.04818Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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