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Mammalian Phenotype (MP): craniofacial phenotype

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   mammalian phenotype [MP:0000001] <29>
0:   craniofacial phenotype [MP:0005382] <1>(20|36) (24|17|10)
- 1:   abnormal craniofacial morphology [MP:0000428] <5>(20|36) (24|17|10)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Homeodomain-like0Direct
p53 tetramerization domain0Direct
SMAD MH1 domain0.000002302Direct
p53-like transcription factors0.0000101Direct
Cystine-knot cytokines0.0001076Direct
Growth factor receptor domain0.0001081Direct
EGF/Laminin0.001272Inherited
FnI-like domain0.004654Inherited
Intermediate filament protein, coiled coil region0.005168Inherited
TB module/8-cys domain0.01008Inherited
Bromodomain0.03369Inherited
Metalloproteases ("zincins"), catalytic domain0.03972Inherited
PGBD-like0.06894Inherited
Nuclear receptor ligand-binding domain0.08607Inherited
Hemopexin-like domain0.1146Inherited
lambda repressor-like DNA-binding domains0.1693Inherited
(Trans)glycosidases0.1887Inherited
Transducin (alpha subunit), insertion domain0.2291Inherited
4-helical cytokines0.3236Inherited
Family A G protein-coupled receptor-like1Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
Retinoblastoma tumor suppressor domains0Direct
p53 tetramerization domain0Direct
Homeodomain0.000000000000007866Direct
SMAD MH1 domain0.000001558Direct
SMAD domain0.000001558Direct
Paired domain0.00001037Direct
Forkhead DNA-binding domain0.0001756Direct
T-box0.0007703Direct
Transforming growth factor (TGF)-beta0.000886Direct
CalX-beta domain0.0009042Direct
Growth factor receptor domain0.001262Inherited
Arylsulfatase0.002029Inherited
Multidrug efflux transporter AcrB transmembrane domain0.002133Inherited
TNF receptor-like0.002544Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.003901Inherited
Intermediate filament protein, coiled coil region0.004579Inherited
Laminin-type module0.005626Inherited
TB module/8-cys domain0.007797Inherited
Pyridoxal-dependent decarboxylase0.01529Inherited
VWC domain0.01539Inherited
Extracellular domain of cell surface receptors0.02087Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.02163Inherited
Ephrin ectodomain0.02674Inherited
Neutral endopeptidase (neprilysin)0.02674Inherited
Bromodomain0.02965Inherited
MMP N-terminal domain0.06038Inherited
I set domains0.06436Inherited
Nuclear receptor0.06503Inherited
Matrix metalloproteases, catalytic domain0.07357Inherited
Nuclear receptor ligand-binding domain0.0814Inherited
Hemopexin-like domain0.104Inherited
DEATH domain, DD0.1279Inherited
Transducin (alpha subunit), insertion domain0.2124Inherited
G proteins0.4182Inherited
Rhodopsin-like1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Homeodomain-like0Direct
p53 tetramerization domain0Direct
SMAD MH1 domain0.0000009579Direct
p53-like transcription factors0.000004437Direct
Cystine-knot cytokines0.00005227Direct
Growth factor receptor domain0.00005254Direct
CalX-like0.0006932Direct
EGF/Laminin0.0007061Direct
Protein kinase-like (PK-like)0.0008942Direct
FnI-like domain0.002771Inherited
Intermediate filament protein, coiled coil region0.003099Inherited
TB module/8-cys domain0.0063Inherited
Orange domain-like0.02285Inherited
Bromodomain0.0231Inherited
Metalloproteases ("zincins"), catalytic domain0.02755Inherited
PGBD-like0.05036Inherited
Nuclear receptor ligand-binding domain0.06401Inherited
Snake toxin-like0.06593Inherited
Hemopexin-like domain0.08803Inherited
lambda repressor-like DNA-binding domains0.1355Inherited
(Trans)glycosidases0.1531Inherited
Transducin (alpha subunit), insertion domain0.1903Inherited
4-helical cytokines0.2793Inherited
Family A G protein-coupled receptor-like1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0004343Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.0005479Direct
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.001224Inherited
    46579,64593
  • 46579 - Prefoldin
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.001744Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.002008Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.003041Inherited
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.003135Inherited
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.008302Inherited
    57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.0128Inherited
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.0128Inherited
    141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0.0128Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.02285Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.03313Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.05036Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.07426Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1632Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.00007584Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.0005661Direct
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.001224Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.002475Inherited
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.003135Inherited
    57196,57196,57581
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.005906Inherited
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.005906Inherited
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.0128Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.02278Inherited
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.03573Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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