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Mammalian Phenotype (MP): abnormal body composition

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   mammalian phenotype [MP:0000001] <29>
+ 1:   growth/size/body region phenotype [MP:0005378] <12>(64|95) (71|47|27)
0:   abnormal body composition [MP:0005451] <5>(20|31) (24|15|9)
- 1:   abnormal body fat mass [MP:0012320] <2>(0|0) (0|0|0)
- 1:   abnormal body mass index [MP:0020182] <2>(0|0) (0|0|0)
- 1:   abnormal body water content [MP:0000676] <2>(0|0) (0|0|0)
- 1:   abnormal lean body mass [MP:0003959] <2>(6|7) (7|5|4)
- 1:   abnormal total tissue mass [MP:0012321] <2>(16|26) (19|12|6)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
N-acetylmuramoyl-L-alanine amidase-like0Direct
Guanido kinase N-terminal domain0Direct
FtsH protease domain-like0Direct
p53 tetramerization domain0Direct
Assembly domain of cartilage oligomeric matrix protein0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Flavoproteins0.001111Inherited
FabD/lysophospholipase-like0.001716Inherited
Macro domain-like0.02603Inherited
SH2 domain0.03551Inherited
Family A G protein-coupled receptor-like0.1042Inherited
Hormone receptor domain0.1135Inherited
STAT0.1731Inherited
Transcription factor STAT-4 N-domain0.1731Inherited
GroEL equatorial domain-like0.2468Inherited
GroEL apical domain-like0.2468Inherited
Hect, E3 ligase catalytic domain0.3189Inherited
Acid proteases0.3594Inherited
Chromo domain-like0.4989Inherited
Clathrin adaptor appendage domain0.6496Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0Direct
Guanido kinase catalytic domain0Direct
Retinoblastoma tumor suppressor domains0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
RUNT domain0Direct
CPH domain0Direct
Assembly domain of cartilage oligomeric matrix protein0Direct
NADPH-cytochrome p450 reductase-like0Direct
PAS domain of steroid receptor coactivator 1A, NCo-A10Direct
p53 tetramerization domain0Direct
Guanido kinase N-terminal domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
FtsH protease domain-like0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.0000005507Direct
Phoshoinositide 3-kinase (PI3K) helical domain0.000771Direct
Pepsin-like0.007042Inherited
Phosphate binding protein-like0.00868Inherited
Macro domain0.02008Inherited
SH2 domain0.03686Inherited
Hormone receptor domain0.09533Inherited
Rhodopsin-like0.107Inherited
STAT DNA-binding domain0.1477Inherited
STAT0.1477Inherited
Transcription factor STAT-4 N-domain0.1477Inherited
gamma-adaptin C-terminal appendage domain-like0.2175Inherited
Hect, E3 ligase catalytic domain0.2937Inherited
DEP domain0.3291Inherited
VHS domain0.436Inherited
Chromo domain0.6002Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
FtsH protease domain-like0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
p53 tetramerization domain0Direct
Guanido kinase N-terminal domain0Direct
Assembly domain of cartilage oligomeric matrix protein0Direct
Flavoproteins0.0006105Direct
FabD/lysophospholipase-like0.0009679Direct
Macro domain-like0.01745Inherited
SH2 domain0.02443Inherited
Riboflavin synthase domain-like0.0269Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0269Inherited
Family A G protein-coupled receptor-like0.07901Inherited
Hormone receptor domain0.08704Inherited
STAT0.1389Inherited
Transcription factor STAT-4 N-domain0.1389Inherited
ENTH/VHS domain0.1777Inherited
GroEL equatorial domain-like0.2068Inherited
GroEL apical domain-like0.2068Inherited
Hect, E3 ligase catalytic domain0.2748Inherited
CAD & PB1 domains0.3032Inherited
Acid proteases0.3137Inherited
Chromo domain-like0.4512Inherited
Clathrin adaptor appendage domain0.6061Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54637,54637
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0Direct
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    52540,140990
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 140990 - FtsH protease domain-like
  • 0Direct
    48034,55931
  • 48034 - Guanido kinase N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 0Direct
    49265,53300
  • 49265 - Fibronectin type III
  • 53300 - vWA-like
  • 0Direct
    54236,57889
  • 54236 - Ubiquitin-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.0006105Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0009679Direct
    111418,81321
  • 111418 - Hormone receptor domain
  • 81321 - Family A G protein-coupled receptor-like
  • 0.01084Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.07506Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.1389Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.1389Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.1389Inherited
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.4201Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57850,49599,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0Direct
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    49265,49265,53300
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 53300 - vWA-like
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0006105Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.07506Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.07506Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.1389Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.1389Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)