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Mammalian Phenotype (MP): abnormal muscle contractility

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   muscle phenotype [MP:0005369] <2>(49|57) (54|37|28)
+ 1:   abnormal muscle physiology [MP:0002106] <23>(25|33) (27|16|11)
0:   abnormal muscle contractility [MP:0005620] <3>(12|15) (13|10|7)
- 1:   impaired muscle contractility [MP:0000738] <3>(12|14) (13|10|7)
- 1:   abnormal cardiac muscle contractility [MP:0002972] <2>(6|8) (7|3|3)
- 1:   abnormal vasoconstriction [MP:0000250] <2>(1|1) (1|1|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
SRF-like0.00015Direct
Inhibitor of apoptosis (IAP) repeat0.002411Inherited
Flavoproteins0.002411Inherited
Myosin rod fragments0.04044Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.06866Inherited
Transducin (alpha subunit), insertion domain0.07133Inherited
Riboflavin synthase domain-like0.07133Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.07133Inherited
Calcium ATPase, transduction domain A0.1361Inherited
Calcium ATPase, transmembrane domain M0.1361Inherited
IP3 receptor type 1 binding core, domain 20.2639Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
L domain0.00009893Direct
SRF-like0.0001012Direct
Cytochrome p450 reductase N-terminal domain-like0.0001012Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.000275Direct
NADPH-cytochrome p450 reductase-like0.000387Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.000387Direct
Inhibitor of apoptosis (IAP) repeat0.0009263Direct
Myosin rod fragments0.03125Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.05581Inherited
Calcium ATPase, transmembrane domain M0.05581Inherited
Transducin (alpha subunit), insertion domain0.05714Inherited
Meta-cation ATPase, catalytic domain P0.117Inherited
Calcium ATPase, transduction domain A0.117Inherited
LIM domain0.1951Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
SRF-like0.00007485Direct
Flavoproteins0.001382Inherited
Inhibitor of apoptosis (IAP) repeat0.001382Inherited
Myosin rod fragments0.02812Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.05014Inherited
Riboflavin synthase domain-like0.05224Inherited
Transducin (alpha subunit), insertion domain0.05224Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.05224Inherited
dsRNA-binding domain-like0.09575Inherited
Calcium ATPase, transmembrane domain M0.1066Inherited
Calcium ATPase, transduction domain A0.1066Inherited
IP3 receptor type 1 binding core, domain 20.2225Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
100909,49899
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.00006936Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00006936Direct
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.0002933Direct
    90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0.02812Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.05014Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.05014Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.05224Inherited
    82109,82109
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 0.2225Inherited
    82109,100909
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.2225Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    82109,100909,49899
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    90257,90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0.000004671Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00006936Direct
    57924,57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.0002933Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.05014Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.1638Inherited
    82109,82109,100909
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.2225Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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