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Mammalian Phenotype (MP): decreased apoptosis

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   cellular phenotype [MP:0005384] <6>(95|116) (103|56|31)
+ + + 3:   abnormal cell physiology [MP:0005621] <24>(77|96) (84|46|25)
+ + 2:   abnormal cell death [MP:0000313] <5>(29|41) (33|15|5)
+ 1:   abnormal apoptosis [MP:0001648] <30>(27|38) (30|13|5)
+ 1:   decreased cell death [MP:0012555] <1>(4|5) (5|3|1)
0:   decreased apoptosis [MP:0006043] <18>(3|5) (5|3|1)
- 1:   decreased kidney apoptosis [MP:0011371] <4>(0|0) (0|0|0)
- 1:   decreased T cell apoptosis [MP:0006414] <3>(1|1) (1|0|0)
- 1:   decreased neuron apoptosis [MP:0003204] <1>(0|1) (1|1|0)
- 1:   decreased B cell apoptosis [MP:0008783](0|0) (0|0|0)
- 1:   decreased activation-induced B cell apoptosis [MP:0010675](0|0) (0|0|0)
- 1:   decreased activation-induced cell death of T cells [MP:0010677](0|0) (0|0|0)
- 1:   decreased anoikis [MP:0011811](0|0) (0|0|0)
- 1:   decreased cardiomyocyte apoptosis [MP:0003223](0|0) (0|0|0)
- 1:   decreased chondrocyte apoptosis [MP:0014104](0|0) (0|0|0)
- 1:   decreased dendritic cell apoptosis [MP:0013260](0|0) (0|0|0)
- 1:   decreased embryonic tissue cell apoptosis [MP:0013505](0|0) (0|0|0)
- 1:   decreased fetal cardiomyocyte apoptosis [MP:0011393](0|0) (0|0|0)
- 1:   decreased fibroblast apoptosis [MP:0013502](0|0) (0|0|0)
- 1:   decreased hair follicle apoptosis [MP:0011196](0|0) (0|0|0)
- 1:   decreased hepatocyte apoptosis [MP:0008891](0|0) (0|0|0)
- 1:   decreased keratinocyte apoptosis [MP:0009581](0|0) (0|0|0)
- 1:   decreased macrophage apoptosis [MP:0011081](0|0) (1|1|0)
- 1:   decreased splenocyte apoptosis [MP:0009341](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
DEATH domain0.00007544Direct
Caspase-like0.0001402Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
p53 tetramerization domain0Direct
Caspase catalytic domain0.0000977Direct
Bcl-2 inhibitors of programmed cell death0.0008744Direct
Toll/Interleukin receptor TIR domain0.02103Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
DEATH domain0.00003608Direct
Caspase-like0.00006965Direct
Bcl-2 inhibitors of programmed cell death0.0007004Direct
Leucine zipper domain0.05922Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.009341Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.02786Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.0005205Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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