SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Mammalian Phenotype (MP): abnormal CD4-positive, alpha beta T cell number

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + + + + 10:   mammalian phenotype [MP:0000001] <29>
+ + + + + + + + 8:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + + + + + 8:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + + + + 7:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(57|86) (66|47|21)
+ + + + + + + 7:   abnormal immune system morphology [MP:0000685] <3>(50|76) (60|35|18)
+ + + + + + 6:   abnormal immune system cell morphology [MP:0000716] <5>(37|63) (48|29|16)
+ + + + + + 6:   abnormal hematopoietic cell morphology [MP:0013656] <9>(48|77) (60|43|18)
+ + + + + 5:   abnormal hematopoietic cell number [MP:0011180] <7>(34|57) (43|29|13)
+ + + + + 5:   abnormal mononuclear cell morphology [MP:0008247] <2>(33|57) (41|28|14)
+ + + + + 5:   abnormal leukocyte morphology [MP:0008246] <4>(36|62) (47|29|15)
+ + + + 4:   abnormal lymphocyte morphology [MP:0002619] <5>(27|46) (33|26|14)
+ + + + 4:   abnormal leukocyte cell number [MP:0000217] <8>(29|49) (37|25|12)
+ + + 3:   abnormal T cell morphology [MP:0008037] <9>(14|25) (18|19|11)
+ + + 3:   abnormal lymphocyte cell number [MP:0000717] <6>(18|38) (25|21|9)
+ + 2:   abnormal T cell number [MP:0006387] <11>(8|22) (16|15|7)
+ + 2:   abnormal alpha-beta T cell morphology [MP:0012762] <13>(7|17) (8|14|6)
+ + 2:   abnormal effector T cell morphology [MP:0002435] <7>(7|16) (8|13|6)
+ 1:   abnormal CD4-positive, alpha beta T cell morphology [MP:0002432] <6>(3|11) (4|10|4)
+ 1:   abnormal alpha-beta T cell number [MP:0012763] <5>(3|11) (4|8|2)
0:   abnormal CD4-positive, alpha beta T cell number [MP:0008073] <9>(1|8) (2|7|2)
- 1:   decreased CD4-positive, alpha beta T cell number [MP:0008075] <8>(1|3) (1|2|1)
- 1:   increased CD4-positive, alpha beta T cell number [MP:0008074] <7>(0|1) (1|0|0)
- 1:   abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number [MP:0012773] <4>(0|0) (0|0|0)
- 1:   abnormal CD4-positive, alpha-beta memory T cell number [MP:0012769] <4>(0|0) (0|0|0)
- 1:   abnormal KLRG1+ CD4 alpha beta T cell number [MP:0013156] <2>(0|0) (0|0|0)
- 1:   abnormal T follicular helper cell number [MP:0010185] <2>(0|0) (0|0|0)
- 1:   abnormal T-helper 1 cell number [MP:0008085] <2>(0|0) (0|0|0)
- 1:   abnormal T-helper 17 cell number [MP:0010218] <2>(0|1) (0|0|0)
- 1:   abnormal T-helper 2 cell number [MP:0008089] <2>(0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Integrin domains0.002821Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Phoshoinositide 3-kinase (PI3K), catalytic domain0.000001446Direct
Interleukin 17F, IL-17F0.000008427Direct
Phoshoinositide 3-kinase (PI3K) helical domain0.0001147Direct
Integrin domains0.001945Inherited
TNF receptor-like0.006766Inherited
V set domains (antibody variable domain-like)0.169Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.2799Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.5374Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Integrin domains0.001633Inherited
TNF receptor-like0.01382Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.00009628Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.000417Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.000417Direct
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.0009048Direct
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.0009048Direct
    53300,69318
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 0.002998Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.2746Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.00009628Direct
    53300,69318,69179
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.002998Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)