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Mammalian Phenotype (MP): abnormal CD4-positive T cell differentiation

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + + + + 10:   mammalian phenotype [MP:0000001] <29>
+ + + + + + + + 8:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + + + + 7:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(57|86) (66|47|21)
+ + + + + + 6:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + + + 6:   abnormal blood cell morphology/development [MP:0002429] <3>(26|35) (28|24|9)
+ + + + + + 6:   abnormal hematopoietic cell morphology [MP:0013656] <9>(48|77) (60|43|18)
+ + + + + + 6:   abnormal blood cell morphology [MP:0013657] <4>(31|49) (37|35|14)
+ + + + + 5:   abnormal leukocyte morphology [MP:0008246] <4>(36|62) (47|29|15)
+ + + + + 5:   abnormal hemopoiesis [MP:0013693] <2>(25|34) (27|24|9)
+ + + + + 5:   abnormal immune system morphology [MP:0000685] <3>(50|76) (60|35|18)
+ + + + 4:   abnormal immune system cell morphology [MP:0000716] <5>(37|63) (48|29|16)
+ + + + 4:   abnormal definitive hematopoiesis [MP:0002123] <4>(24|34) (26|24|9)
+ + + + 4:   abnormal mononuclear cell morphology [MP:0008247] <2>(33|57) (41|28|14)
+ + + 3:   abnormal leukopoiesis [MP:0005460] <3>(17|28) (21|18|8)
+ + + 3:   abnormal lymphocyte morphology [MP:0002619] <5>(27|46) (33|26|14)
+ + 2:   abnormal T cell morphology [MP:0008037] <9>(14|25) (18|19|11)
+ + 2:   abnormal alpha-beta T cell morphology [MP:0012762] <13>(7|17) (8|14|6)
+ + 2:   abnormal effector T cell morphology [MP:0002435] <7>(7|16) (8|13|6)
+ + 2:   abnormal lymphopoiesis [MP:0002401] <3>(17|25) (21|15|6)
+ 1:   abnormal T cell differentiation [MP:0002145] <9>(6|9) (10|8|3)
+ 1:   abnormal CD4-positive, alpha beta T cell morphology [MP:0002432] <6>(3|11) (4|10|4)
0:   abnormal CD4-positive T cell differentiation [MP:0008076] <3>(0|3) (2|3|2)
- 1:   abnormal T follicular helper cell differentiation [MP:0010188](0|0) (0|0|0)
- 1:   abnormal T-helper 1 cell differentiation [MP:0008088](0|0) (0|0|0)
- 1:   abnormal T-helper 2 cell differentiation [MP:0008092](0|0) (0|0|0)


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
STAT DNA-binding domain0.0006551Direct
STAT0.0006551Direct
Transcription factor STAT-4 N-domain0.0006551Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
STAT0.0005491Direct
Transcription factor STAT-4 N-domain0.0005491Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0005491Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.0005491Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0005491Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0005491Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0005491Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)