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Mammalian Phenotype (MP): abnormal CD8-positive, alpha-beta T cell number

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + + + + 10:   mammalian phenotype [MP:0000001] <29>
+ + + + + + + + 8:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + + + + + 8:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + + + + 7:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(57|86) (66|47|21)
+ + + + + + + 7:   abnormal immune system morphology [MP:0000685] <3>(50|76) (60|35|18)
+ + + + + + 6:   abnormal hematopoietic cell morphology [MP:0013656] <9>(48|77) (60|43|18)
+ + + + + + 6:   abnormal immune system cell morphology [MP:0000716] <5>(37|63) (48|29|16)
+ + + + + 5:   abnormal hematopoietic cell number [MP:0011180] <7>(34|57) (43|29|13)
+ + + + + 5:   abnormal mononuclear cell morphology [MP:0008247] <2>(33|57) (41|28|14)
+ + + + + 5:   abnormal leukocyte morphology [MP:0008246] <4>(36|62) (47|29|15)
+ + + + 4:   abnormal leukocyte cell number [MP:0000217] <8>(29|49) (37|25|12)
+ + + + 4:   abnormal lymphocyte morphology [MP:0002619] <5>(27|46) (33|26|14)
+ + + 3:   abnormal T cell morphology [MP:0008037] <9>(14|25) (18|19|11)
+ + + 3:   abnormal lymphocyte cell number [MP:0000717] <6>(18|38) (25|21|9)
+ + 2:   abnormal T cell number [MP:0006387] <11>(8|22) (16|15|7)
+ + 2:   abnormal alpha-beta T cell morphology [MP:0012762] <13>(7|17) (8|14|6)
+ + 2:   abnormal effector T cell morphology [MP:0002435] <7>(7|16) (8|13|6)
+ 1:   abnormal alpha-beta T cell number [MP:0012763] <5>(3|11) (4|8|2)
+ 1:   abnormal CD8-positive, alpha beta T cell morphology [MP:0005010] <7>(3|8) (3|6|2)
0:   abnormal CD8-positive, alpha-beta T cell number [MP:0008077] <6>(2|7) (2|5|2)
- 1:   decreased CD8-positive, alpha-beta T cell number [MP:0008079] <5>(2|5) (2|2|0)
- 1:   abnormal CD8-positive, alpha-beta memory T cell number [MP:0012774] <4>(0|0) (0|0|0)
- 1:   increased CD8-positive, alpha-beta T cell number [MP:0008078] <4>(0|0) (0|1|1)
- 1:   abnormal CD8-positive, CD25-positive alpha-beta T cell number [MP:0013888] <2>(0|0) (0|0|0)
- 1:   abnormal CD8-positive, naive alpha-beta T cell number [MP:0013434] <2>(0|0) (0|0|0)
- 1:   abnormal KLRG1+ CD8 alpha beta T cell number [MP:0013153] <2>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.001121Inherited
MHC antigen-recognition domain0.6844Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Proteasome subunits0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.0000004604Direct
Phoshoinositide 3-kinase (PI3K) helical domain0.0000591Direct
Rel/Dorsal transcription factors, DNA-binding domain0.1877Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.1877Inherited
C1 set domains (antibody constant domain-like)0.4786Inherited
MHC antigen-recognition domain0.6489Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0006158Direct
MHC antigen-recognition domain0.6427Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.00004879Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0002193Direct
    53300,69318
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 0.001835Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.1831Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.6427Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.00004879Direct
    53300,69318,69179
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.001835Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)