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Mammalian Phenotype (MP): abnormal professional antigen presenting cell morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + 2:   abnormal immune system morphology [MP:0000685] <3>(50|76) (60|35|18)
+ 1:   abnormal immune system cell morphology [MP:0000716] <5>(37|63) (48|29|16)
0:   abnormal professional antigen presenting cell morphology [MP:0008195] <3>(16|32) (20|11|5)
- 1:   abnormal macrophage morphology [MP:0002446] <14>(6|12) (8|4|0)
- 1:   abnormal mature B cell morphology [MP:0008171] <9>(8|21) (10|8|4)
- 1:   abnormal dendritic cell morphology [MP:0005461] <4>(2|4) (2|1|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Triple coiled coil domain of C-type lectins0.002554Inherited
WWE domain0.02918Inherited
Ran binding protein zinc finger-like0.03341Inherited
DEATH domain0.06082Inherited
p53-like transcription factors0.06473Inherited
Nuclear receptor ligand-binding domain0.06838Inherited
SH2 domain0.07747Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.1051Inherited
Riboflavin synthase domain-like0.1051Inherited
Bcl-2 inhibitors of programmed cell death0.1266Inherited
Calponin-homology domain, CH-domain0.2506Inherited
SMAD/FHA domain0.2938Inherited
DBL homology domain (DH-domain)0.3284Inherited
Flavoproteins0.3826Inherited
Toll/Interleukin receptor TIR domain0.4976Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
RUNT domain0Direct
BAFF receptor-like0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Rel/Dorsal transcription factors, DNA-binding domain0.0000009516Direct
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.000006668Direct
Triple coiled coil domain of C-type lectins0.00169Inherited
beta-glycanases0.00169Inherited
Cytochrome p450 reductase N-terminal domain-like0.00169Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.005701Inherited
Tetraspanin0.005701Inherited
NADPH-cytochrome p450 reductase-like0.005701Inherited
WWE domain0.01245Inherited
Interferon regulatory factor 3 (IRF3), transactivation domain0.02202Inherited
Ran binding protein zinc finger-like0.02476Inherited
Nuclear receptor ligand-binding domain0.05459Inherited
Nuclear receptor0.05459Inherited
SH2 domain0.06481Inherited
Caspase recruitment domain, CARD0.08754Inherited
Pointed domain0.1037Inherited
Bcl-2 inhibitors of programmed cell death0.1037Inherited
Interferon regulatory factor0.1037Inherited
PLC-like (P variant)0.1482Inherited
MATH domain0.164Inherited
Pleckstrin-homology domain (PH domain)0.1819Inherited
Calponin-homology domain, CH-domain0.2306Inherited
DEATH domain, DD0.2314Inherited
Long-chain cytokines0.245Inherited
DBL homology domain (DH-domain)0.2968Inherited
Higher-molecular-weight phosphotyrosine protein phosphatases0.3431Inherited
Toll/Interleukin receptor TIR domain0.3431Inherited
CCCH zinc finger0.3484Inherited
V set domains (antibody variable domain-like)0.3766Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Triple coiled coil domain of C-type lectins0.00147Inherited
WWE domain0.01978Inherited
Ran binding protein zinc finger-like0.02288Inherited
DEATH domain0.04384Inherited
p53-like transcription factors0.04695Inherited
Nuclear receptor ligand-binding domain0.0499Inherited
SH2 domain0.05702Inherited
TNF-like0.07334Inherited
Riboflavin synthase domain-like0.07979Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.07979Inherited
Bcl-2 inhibitors of programmed cell death0.09824Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.1184Inherited
Calponin-homology domain, CH-domain0.2104Inherited
SMAD/FHA domain0.2509Inherited
DBL homology domain (DH-domain)0.2839Inherited
CCCH zinc finger0.3364Inherited
Flavoproteins0.3364Inherited
Toll/Interleukin receptor TIR domain0.4499Inherited
Immunoglobulin0.9105Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.0000006615Direct
    57944,56436
  • 57944 - Triple coiled coil domain of C-type lectins
  • 56436 - C-type lectin-like
  • 0.00147Inherited
    57850,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 0.03104Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.06379Inherited
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.09824Inherited
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.09824Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.1265Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.2354Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.2354Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.2839Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50729,50044,55550
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0Direct
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0002409Direct
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.1571Inherited
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.1571Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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