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Mammalian Phenotype (MP): abnormal B cell activation

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   mammalian phenotype [MP:0000001] <29>
+ + + + + + 6:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + + 5:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + + 5:   abnormal hematopoietic system physiology [MP:0001545] <5>(39|53) (40|38|21)
+ + + + 4:   abnormal immune system physiology [MP:0001790] <16>(59|84) (66|49|28)
+ + + + 4:   abnormal blood cell physiology [MP:0012382] <3>(38|53) (39|38|21)
+ + + 3:   abnormal cell-mediated immunity [MP:0002421] <3>(35|48) (37|33|21)
+ + + 3:   abnormal leukocyte physiology [MP:0002442] <5>(34|48) (36|33|20)
+ + + 3:   abnormal immune cell physiology [MP:0001819] <3>(35|48) (37|33|21)
+ + + 3:   abnormal adaptive immunity [MP:0002420] <8>(36|48) (38|33|21)
+ + 2:   abnormal lymphocyte physiology [MP:0003945] <4>(21|31) (23|22|13)
+ + 2:   abnormal professional antigen presenting cell physiology [MP:0002452] <3>(25|32) (26|19|12)
+ 1:   abnormal B cell physiology [MP:0002459] <9>(19|27) (20|16|10)
0:   abnormal B cell activation [MP:0008217] <1>(7|11) (7|6|1)
- 1:   abnormal B cell proliferation [MP:0005153] <2>(7|11) (7|6|1)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
WWE domain0.0002523Direct
E set domains0.0006329Direct
SH2 domain0.01879Inherited
DBL homology domain (DH-domain)0.02716Inherited
SH3-domain0.06983Inherited
Toll/Interleukin receptor TIR domain0.1321Inherited
p53-like transcription factors0.1564Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
WWE domain0.00006921Direct
ets domain0.004607Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.007145Inherited
SH2 domain0.009659Inherited
DBL homology domain (DH-domain)0.01666Inherited
Pleckstrin-homology domain (PH domain)0.01729Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.01813Inherited
PLC-like (P variant)0.03579Inherited
SH3-domain0.04251Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain0.1482Inherited
Toll/Interleukin receptor TIR domain0.1574Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
WWE domain0.0001286Direct
E set domains0.0003376Direct
SH2 domain0.01225Inherited
DBL homology domain (DH-domain)0.01827Inherited
SH3-domain0.05104Inherited
Toll/Interleukin receptor TIR domain0.103Inherited
p53-like transcription factors0.1243Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.00001371Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.008001Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.01827Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.03209Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.03991Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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