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Mammalian Phenotype (MP): abnormal myeloid leukocyte morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + 4:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + 3:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(57|86) (66|47|21)
+ + + 3:   abnormal immune system morphology [MP:0000685] <3>(50|76) (60|35|18)
+ + 2:   abnormal immune system cell morphology [MP:0000716] <5>(37|63) (48|29|16)
+ + 2:   abnormal hematopoietic cell morphology [MP:0013656] <9>(48|77) (60|43|18)
+ 1:   abnormal leukocyte morphology [MP:0008246] <4>(36|62) (47|29|15)
+ 1:   abnormal myeloid cell morphology [MP:0013658] <8>(19|41) (26|23|8)
0:   abnormal myeloid leukocyte morphology [MP:0008250] <2>(11|24) (16|10|2)
- 1:   abnormal granulocyte morphology [MP:0002441] <6>(4|8) (6|6|2)
- 1:   abnormal phagocyte morphology [MP:0008251] <3>(10|21) (13|9|1)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
p53-like transcription factors0.00002666Direct
Flavoproteins0.0002721Direct
Triple coiled coil domain of C-type lectins0.002169Inherited
Nuclear receptor ligand-binding domain0.0133Inherited
TIMP-like0.02339Inherited
DEATH domain0.03791Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.09345Inherited
Riboflavin synthase domain-like0.09345Inherited
Terpenoid cyclases/Protein prenyltransferases0.1247Inherited
TNF receptor-like0.3424Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
RUNT domain0Direct
Cytochrome p450 reductase N-terminal domain-like0.001419Inherited
Triple coiled coil domain of C-type lectins0.001419Inherited
Tissue inhibitor of metalloproteinases, TIMP0.001419Inherited
beta-glycanases0.001419Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.001991Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.004246Inherited
Tetraspanin0.004825Inherited
NADPH-cytochrome p450 reductase-like0.004825Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.004825Inherited
Long-chain cytokines0.008845Inherited
Nuclear receptor ligand-binding domain0.009355Inherited
Nuclear receptor0.009355Inherited
Interferons/interleukin-10 (IL-10)0.05664Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain0.06962Inherited
Interleukin-1 (IL-1)0.07225Inherited
Pyrin domain, PYD0.1011Inherited
Short-chain cytokines0.1262Inherited
TNF receptor-like0.1272Inherited
Interleukin 17F, IL-17F0.1742Inherited
Phoshoinositide 3-kinase (PI3K) helical domain0.1742Inherited
C2 set domains0.2913Inherited
Integrin domains0.3991Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
p53-like transcription factors0.00001218Direct
Flavoproteins0.0001392Direct
Triple coiled coil domain of C-type lectins0.001237Inherited
(Trans)glycosidases0.006562Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.008089Inherited
Nuclear receptor ligand-binding domain0.008468Inherited
TIMP-like0.01554Inherited
DEATH domain0.0262Inherited
Riboflavin synthase domain-like0.07006Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.07006Inherited
Terpenoid cyclases/Protein prenyltransferases0.09657Inherited
C-type lectin-like0.2178Inherited
TNF receptor-like0.2971Inherited
TNF-like0.3877Inherited
Integrin domains0.3877Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.00002711Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.0009368Direct
    57944,56436
  • 57944 - Triple coiled coil domain of C-type lectins
  • 56436 - C-type lectin-like
  • 0.001237Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.003877Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.07334Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.09657Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.1682Inherited
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.1682Inherited
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.1682Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.2651Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.02624Inherited
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.1682Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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