SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Mammalian Phenotype (MP): increased sensitivity to induced cell death

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   cellular phenotype [MP:0005384] <6>(95|116) (103|56|31)
+ + + 3:   abnormal cell physiology [MP:0005621] <24>(77|96) (84|46|25)
+ + 2:   abnormal cell death [MP:0000313] <5>(29|41) (33|15|5)
+ 1:   abnormal induced cell death [MP:0008942] <2>(5|6) (6|3|0)
0:   increased sensitivity to induced cell death [MP:0008943] <4>(3|3) (3|2|0)
- 1:   increased cellular sensitivity to DNA damaging agents [MP:0014040] <2>(0|0) (0|0|0)
- 1:   increased cellular sensitivity to ionizing radiation [MP:0004227] <2>(1|1) (1|2|0)
- 1:   increased cellular sensitivity to oxidative stress [MP:0008412] <1>(1|1) (1|0|0)
- 1:   increased cellular sensitivity to ultraviolet irradiation [MP:0008410](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
BRCT domain0.0000006188Direct
DHS-like NAD/FAD-binding domain0.0004635Direct
Thioredoxin-like0.2562Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Sir2 family of transcriptional regulators0.00009052Direct
Glutathione peroxidase-like0.0001791Direct
FHA domain0.3527Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
BRCT domain0.00000025Direct
DHS-like NAD/FAD-binding domain0.0002435Direct
Thioredoxin-like0.2154Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.00000149Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2154Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)