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Mammalian Phenotype (MP): decreased neuron number

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   nervous system phenotype [MP:0003631] <2>(98|128) (113|79|50)
+ + + 3:   abnormal nervous system morphology [MP:0003632] <17>(76|104) (91|64|47)
+ + 2:   abnormal neuron morphology [MP:0002882] <29>(36|59) (40|26|19)
+ 1:   abnormal neuron number [MP:0008946] <3>(8|16) (9|9|8)
0:   decreased neuron number [MP:0008948] <8>(6|11) (6|5|4)
- 1:   decreased sensory neuron number [MP:0000966] <6>(5|8) (5|3|2)
- 1:   decreased Cajal-Retzius cell number [MP:0008031] <1>(0|0) (0|0|0)
- 1:   decreased cerebellar granule cell number [MP:0008924] <1>(0|0) (0|0|0)
- 1:   decreased cerebral cortex pyramidal cell number [MP:0009974] <1>(0|0) (0|0|0)
- 1:   decreased hippocampus pyramidal cell number [MP:0009971] <1>(0|0) (0|0|0)
- 1:   decreased Purkinje cell number [MP:0000880](0|0) (0|0|0)
- 1:   decreased dopaminergic neuron number [MP:0011448](0|0) (0|0|0)
- 1:   decreased motor neuron number [MP:0000939](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Proton glutamate symport protein0.0001855Direct
GAF domain-like0.001551Inherited
E2F-DP heterodimerization region0.002909Inherited
HD-domain/PDEase-like0.06345Inherited
Cyclin-like0.1297Inherited
HLH, helix-loop-helix DNA-binding domain0.6481Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Retinoblastoma tumor suppressor domains0Direct
Neurotrophin0.0001224Direct
Proton glutamate symport protein0.0001224Direct
L domain0.0001248Direct
GAF domain0.001108Inherited
E2F dimerization segment0.001108Inherited
Cell cycle transcription factor e2f-dp0.005576Inherited
Laminin-type module0.01144Inherited
PDEase0.04052Inherited
cAMP-binding domain0.04072Inherited
HLH, helix-loop-helix DNA-binding domain0.5645Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Proton glutamate symport protein0.00009343Direct
GAF domain-like0.0008688Direct
E2F-DP heterodimerization region0.001686Inherited
HD-domain/PDEase-like0.04596Inherited
Cyclin-like0.1009Inherited
HLH, helix-loop-helix DNA-binding domain0.6045Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.00009102Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00009102Direct
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.0008688Direct
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.0008688Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.001686Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00009102Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.00009343Direct
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.0008688Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)