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Mammalian Phenotype (MP): abnormal internal male genitalia morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   reproductive system phenotype [MP:0005389] <2>(38|58) (47|18|6)
+ + + 3:   abnormal reproductive system morphology [MP:0002160] <12>(28|46) (37|15|6)
+ + 2:   abnormal male reproductive system morphology [MP:0001145] <2>(12|18) (15|4|0)
+ 1:   abnormal male genitalia morphology [MP:0009198] <2>(12|18) (15|4|0)
0:   abnormal internal male genitalia morphology [MP:0009205] <10>(12|17) (15|4|0)
- 1:   abnormal testis morphology [MP:0001146] <15>(9|15) (11|4|0)
- 1:   abnormal epididymis morphology [MP:0002631] <10>(3|3) (4|0|0)
- 1:   abnormal prostate gland morphology [MP:0001158] <10>(0|0) (0|1|0)
- 1:   abnormal seminal vesicle morphology [MP:0002059] <9>(1|0) (1|1|0)
- 1:   abnormal bulbourethral gland morphology [MP:0001169] <7>(0|0) (0|0|0)
- 1:   abnormal vas deferens morphology [MP:0002769] <3>(3|3) (3|1|0)
- 1:   abnormal spermatic cord morphology [MP:0010145](0|0) (0|0|0)
- 1:   absent internal male genitalia [MP:0009206](0|0) (0|0|0)
- 1:   internal male genitalia hypoplasia [MP:0009207](0|0) (0|0|0)
- 1:   spermatocele [MP:0014187](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nuclear receptor ligand-binding domain0.000001449Direct
Cystine-knot cytokines0.00001568Direct
E2F-DP heterodimerization region0.00008794Direct
Tudor/PWWP/MBT0.00009722Direct
PAZ domain0.0002624Direct
The spindle assembly checkpoint protein mad20.001058Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.002898Inherited
HMG-box0.07196Inherited
L domain-like0.6243Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.6583Inherited
Homeodomain-like0.6803Inherited
LDL receptor-like module0.929Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nuclear receptor ligand-binding domain0.0000009027Direct
E2F dimerization segment0.000009632Direct
Tudor domain0.00001243Direct
Nuclear receptor0.00001327Direct
Transforming growth factor (TGF)-beta0.0000257Direct
PAZ domain0.0001574Direct
Cell cycle transcription factor e2f-dp0.0003755Direct
The spindle assembly checkpoint protein mad20.0006544Direct
DNA gyrase/MutL, second domain0.0006544Direct
DNA gyrase/MutL, N-terminal domain0.0006544Direct
Single strand DNA-binding domain, SSB0.0009568Direct
Gonadodropin/Follitropin0.002311Inherited
Cysteine-rich DNA binding domain, (DM domain)0.009705Inherited
HMG-box0.05847Inherited
Ngr ectodomain-like0.5041Inherited
Homeodomain0.7049Inherited
LDL receptor-like module0.9108Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nuclear receptor ligand-binding domain0.0000005948Direct
Cystine-knot cytokines0.000006965Direct
E2F-DP heterodimerization region0.0000422Direct
Tudor/PWWP/MBT0.00004681Direct
PAZ domain0.0001342Direct
The spindle assembly checkpoint protein mad20.0005798Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.001678Inherited
Cysteine-rich DNA binding domain, (DM domain)0.008729Inherited
Ribonuclease H-like0.01036Inherited
HMG-box0.05277Inherited
L domain-like0.5796Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.6153Inherited
Homeodomain-like0.6384Inherited
Family A G protein-coupled receptor-like0.7251Inherited
LDL receptor-like module0.9049Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.0000422Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.0003683Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.002069Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.002069Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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