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Mammalian Phenotype (MP): abnormal behavioral response to xenobiotic

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   behavior/neurological phenotype [MP:0005386] <1>(38|61) (42|40|24)
+ 1:   abnormal behavior [MP:0004924] <19>(37|56) (41|37|22)
0:   abnormal behavioral response to xenobiotic [MP:0009745] <11>(8|13) (9|2|0)
- 1:   abnormal behavioral response to addictive substance [MP:0009748] <9>(1|1) (2|0|0)
- 1:   abnormal alcohol consumption [MP:0001425] <5>(2|0) (2|0|0)
- 1:   preference for addictive substance [MP:0002553] <5>(0|0) (0|0|0)
- 1:   abnormal behavioral response to anesthetic [MP:0009777] <2>(0|0) (0|0|0)
- 1:   abnormal seizure response to pharmacological agent [MP:0000950] <2>(1|4) (1|0|0)
- 1:   enhanced behavioral response to xenobiotic [MP:0009746] <2>(0|0) (0|0|0)
- 1:   impaired behavioral response to xenobiotic [MP:0009747] <2>(0|1) (0|0|0)
- 1:   abnormal cocaine consumption [MP:0002556] <1>(0|0) (0|0|0)
- 1:   aversion to addictive substance [MP:0002554] <1>(0|0) (0|0|0)
- 1:   abnormal habituation to xenobiotic [MP:0011623](0|0) (0|0|0)
- 1:   abnormal sensitization to xenobiotic [MP:0011624](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Metallothionein0Direct
Neurotransmitter-gated ion-channel transmembrane pore0.00000000188Direct
Nicotinic receptor ligand binding domain-like0.00000000188Direct
Voltage-gated potassium channels0.000001792Direct
Family A G protein-coupled receptor-like0.000002794Direct
Periplasmic binding protein-like I0.00004641Direct
SNF-like0.00009162Direct
PDZ domain-like0.08972Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Metallothionein0Direct
Nicotinic receptor ligand binding domain-like0.00000000089Direct
Neurotransmitter-gated ion-channel transmembrane pore0.00000000089Direct
Rhodopsin-like0.000000179Direct
SNF-like0.00004861Direct
L-arabinose binding protein-like0.0001539Direct
Phosphate binding protein-like0.0006345Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.0009807Direct
NADPH-cytochrome p450 reductase-like0.0009807Direct
Cytochrome p450 reductase N-terminal domain-like0.0009807Direct
Voltage-gated potassium channels0.001482Inherited
Tetramerization domain of potassium channels0.005843Inherited
PDZ domain0.01549Inherited


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Metallothionein0Direct
Nicotinic receptor ligand binding domain-like0.0000000007028Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0000000007028Direct
Voltage-gated potassium channels0.0000007372Direct
Family A G protein-coupled receptor-like0.000001174Direct
Periplasmic binding protein-like I0.00002174Direct
SNF-like0.00004396Direct
Periplasmic binding protein-like II0.0005921Direct
PDZ domain-like0.06694Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.0000000007028Direct
    81324,53850
  • 81324 - Voltage-gated potassium channels
  • 53850 - Periplasmic binding protein-like II
  • 0.0009171Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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