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Mammalian Phenotype (MP): abnormal neuron differentiation

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   cellular phenotype [MP:0005384] <6>(95|116) (103|56|31)
+ + + 3:   nervous system phenotype [MP:0003631] <2>(98|128) (113|79|50)
+ + 2:   abnormal nervous system morphology [MP:0003632] <17>(76|104) (91|64|47)
+ + 2:   abnormal cell physiology [MP:0005621] <24>(77|96) (84|46|25)
+ 1:   abnormal cell differentiation [MP:0005076] <25>(11|17) (13|5|4)
+ 1:   abnormal neuron morphology [MP:0002882] <29>(36|59) (40|26|19)
+ 1:   abnormal nervous system development [MP:0003861] <9>(19|31) (21|14|10)
0:   abnormal neuron differentiation [MP:0009937] <8>(8|11) (8|2|1)
- 1:   abnormal radial glial cell morphology [MP:0003648] <2>(1|3) (1|0|0)
- 1:   abnormal axon extension [MP:0003651] <1>(1|1) (1|0|0)
- 1:   abnormal Purkinje cell differentiation [MP:0008579](0|0) (0|0|0)
- 1:   abnormal axon fasciculation [MP:0009450](0|0) (0|0|0)
- 1:   abnormal axon guidance [MP:0002961](2|3) (2|2|0)
- 1:   abnormal axon pruning [MP:0008960](1|2) (2|1|0)
- 1:   impaired neuron differentiation [MP:0011827](0|0) (0|0|0)
- 1:   premature neuronal precursor differentiation [MP:0003424](2|2) (2|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Homeodomain-like0.0001894Direct
HLH, helix-loop-helix DNA-binding domain0.0006878Direct
Galactose-binding domain-like0.02272Inherited
Fibronectin type III0.02987Inherited
SNARE fusion complex0.03896Inherited
SAM/Pointed domain0.07896Inherited
RNA-binding domain, RBD0.3993Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Other IPT/TIG domains0Direct
HLH, helix-loop-helix DNA-binding domain0.0006294Direct
Homeodomain0.0007531Direct
Ephrin receptor ligand binding domain0.00373Inherited
Fibronectin type III0.02879Inherited
SAM (sterile alpha motif) domain0.0299Inherited
SNARE fusion complex0.03413Inherited
Enabled/VASP homology 1 domain (EVH1 domain)0.03578Inherited
Forkhead DNA-binding domain0.08443Inherited
Canonical RBD0.2625Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Homeodomain-like0.00009531Direct
HLH, helix-loop-helix DNA-binding domain0.0003676Direct
Galactose-binding domain-like0.01506Inherited
Fibronectin type III0.02032Inherited
SNARE fusion complex0.02698Inherited
SAM/Pointed domain0.05822Inherited
RNA-binding domain, RBD0.3527Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.002957Inherited
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.004716Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0007604Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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