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Mammalian Phenotype (MP): increased gland tumor incidence

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   neoplasm [MP:0002006] <2>(32|37) (38|18|7)
+ + + + 4:   altered tumor susceptibility [MP:0002166] <3>(25|29) (30|11|3)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   abnormal tumor incidence [MP:0002019] <6>(25|29) (30|11|3)
+ + 2:   endocrine/exocrine gland phenotype [MP:0005379] <2>(51|81) (55|36|12)
+ + 2:   increased tumor incidence [MP:0002020] <3>(25|27) (30|10|3)
+ + 2:   abnormal organ/body region tumor incidence [MP:0013152] <2>(21|24) (24|8|3)
+ 1:   increased organ/body region tumor incidence [MP:0010274] <14>(21|24) (24|8|3)
+ 1:   abnormal gland morphology [MP:0002163] <8>(44|71) (50|31|11)
0:   increased gland tumor incidence [MP:0010288] <15>(6|9) (7|2|0)
- 1:   increased mammary gland tumor incidence [MP:0010299] <6>(1|3) (1|2|0)
- 1:   increased pancreas tumor incidence [MP:0009153] <6>(0|0) (0|0|0)
- 1:   increased ovary tumor incidence [MP:0008000] <5>(1|2) (1|0|0)
- 1:   increased pituitary gland tumor incidence [MP:0010320] <4>(1|0) (1|0|0)
- 1:   increased salivary gland tumor incidence [MP:0010318] <4>(1|2) (1|1|0)
- 1:   increased adrenal gland tumor incidence [MP:0002031] <3>(0|0) (0|0|0)
- 1:   increased Harderian gland tumor incidence [MP:0012437] <2>(0|0) (0|0|0)
- 1:   increased prostate gland tumor incidence [MP:0010357] <2>(0|0) (0|0|0)
- 1:   increased testis tumor incidence [MP:0006262] <2>(0|0) (0|0|0)
- 1:   increased thyroid tumor incidence [MP:0010316] <2>(0|0) (0|0|0)
- 1:   increased parathyroid gland tumor incidence [MP:0010321] <1>(0|0) (0|0|0)
- 1:   increased sebaceous gland tumor incidence [MP:0013374] <1>(0|0) (0|0|0)
- 1:   increased thymus tumor incidence [MP:0010365] <1>(3|5) (3|1|0)
- 1:   increased bulbourethral gland adenocarcinoma incidence [MP:0011791](0|0) (0|0|0)
- 1:   increased pineal gland tumor incidence [MP:0013365](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
SMAD/FHA domain0.0001691Direct
SMAD MH1 domain0.0007487Direct
BRCT domain0.002012Inherited
CCCH zinc finger0.005626Inherited
4-helical cytokines0.09585Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
p53 tetramerization domain0Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0.0001124Direct
SMAD MH1 domain0.0005268Direct
SMAD domain0.0005268Direct
DNA polymerase I0.003008Inherited
CCCH zinc finger0.004546Inherited
DnaQ-like 3'-5' exonuclease0.009785Inherited
FHA domain0.02543Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
SMAD/FHA domain0.00008479Direct
SMAD MH1 domain0.0004023Direct
Nucleic acid-binding proteins0.0006533Direct
BRCT domain0.001144Inherited
CCCH zinc finger0.003389Inherited
4-helical cytokines0.07199Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.01747Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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