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Mammalian Phenotype (MP): increased hemolymphoid system tumor incidence

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   mammalian phenotype [MP:0000001] <29>
+ + + + + 5:   neoplasm [MP:0002006] <2>(32|37) (38|18|7)
+ + + + 4:   altered tumor susceptibility [MP:0002166] <3>(25|29) (30|11|3)
+ + + 3:   abnormal tumor incidence [MP:0002019] <6>(25|29) (30|11|3)
+ + 2:   abnormal organ/body region tumor incidence [MP:0013152] <2>(21|24) (24|8|3)
+ + 2:   increased tumor incidence [MP:0002020] <3>(25|27) (30|10|3)
+ 1:   increased organ/body region tumor incidence [MP:0010274] <14>(21|24) (24|8|3)
0:   increased hemolymphoid system tumor incidence [MP:0010296] <7>(10|10) (10|4|1)
- 1:   increased leukemia incidence [MP:0002026] <4>(3|4) (3|3|1)
- 1:   increased lymphoma incidence [MP:0012431] <3>(7|9) (7|3|0)
- 1:   increased Type B reticulum cell tumor incidence [MP:0012412](0|0) (0|0|0)
- 1:   increased myeloid sarcoma incidence [MP:0009439](0|0) (0|0|0)
- 1:   increased myeloma incidence [MP:0009440](0|0) (0|0|0)
- 1:   increased spleen neoplasm incidence [MP:0005649](0|0) (0|0|0)
- 1:   increased thymoma incidence [MP:0014127](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
SPOC domain-like0.00004749Direct
DNA repair protein MutS, domain III0.0001809Direct
SAND domain-like0.0001809Direct
Notch domain0.0001809Direct
Putative DNA-binding domain0.0008514Direct
SET domain0.001476Inherited
CCCH zinc finger0.006015Inherited
BRCT domain0.2158Inherited
p53-like transcription factors0.3511Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
p53 tetramerization domain0Direct
DNA polymerase I0.000007013Direct
Notch domain0.0001154Direct
DNA repair protein MutS, domain III0.0001154Direct
Single strand DNA-binding domain, SSB0.0005729Direct
Histone lysine methyltransferases0.0007243Direct
CCCH zinc finger0.004436Inherited
DnaQ-like 3'-5' exonuclease0.004436Inherited
Phosphotyrosine-binding domain (PTB)0.1195Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
SPOC domain-like0.0000223Direct
DNA repair protein MutS, domain III0.00009101Direct
SAND domain-like0.00009101Direct
Notch domain0.00009101Direct
Putative DNA-binding domain0.0004611Direct
SET domain0.0008268Direct
CCCH zinc finger0.003633Inherited
BRCT domain0.1779Inherited
p53-like transcription factors0.3058Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.0000223Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00009101Direct
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.005575Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.004749Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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