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Mammalian Phenotype (MP): abnormal circulating lipoprotein level

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   homeostasis/metabolism phenotype [MP:0005376] <7>(140|174) (149|96|44)
+ + 2:   abnormal homeostasis [MP:0001764] <27>(103|129) (113|73|31)
+ 1:   abnormal lipoprotein level [MP:0010329] <1>(7|8) (8|4|4)
+ 1:   abnormal blood homeostasis [MP:0009642] <23>(63|82) (70|45|21)
0:   abnormal circulating lipoprotein level [MP:0010330] <4>(7|7) (7|4|3)
- 1:   abnormal circulating HDL cholesterol level [MP:0000184] <2>(1|2) (1|1|0)
- 1:   abnormal circulating LDL cholesterol level [MP:0000181] <2>(5|5) (5|1|0)
- 1:   abnormal circulating VLDL cholesterol level [MP:0005144] <2>(0|0) (0|1|1)
- 1:   hyperchylomicronemia [MP:0009699](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Apolipoprotein A-I0.000002222Direct
Nuclear receptor ligand-binding domain0.0008861Direct
Multidrug efflux transporter AcrB transmembrane domain0.00196Inherited
Flavoproteins0.01345Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.02324Inherited
Riboflavin synthase domain-like0.02324Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Apolipoprotein A-I0Direct
Nuclear receptor ligand-binding domain0.000509Direct
Cytochrome p450 reductase N-terminal domain-like0.001182Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.004074Inherited
Pancreatic lipase, N-terminal domain0.004074Inherited
NADPH-cytochrome p450 reductase-like0.004074Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Apolipoprotein A-I0.0000009221Direct
Nuclear receptor ligand-binding domain0.0004801Direct
Multidrug efflux transporter AcrB transmembrane domain0.001114Inherited
Flavoproteins0.008576Inherited
Riboflavin synthase domain-like0.01543Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.01543Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.0007038Direct
    53474,49723
  • 53474 - alpha/beta-Hydrolases
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0.001114Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.00162Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.0008268Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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