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Mammalian Phenotype (MP): abnormal heart layer morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   cardiovascular system phenotype [MP:0005385] <2>(67|85) (77|57|35)
+ + 2:   abnormal cardiovascular system morphology [MP:0002127] <7>(48|65) (53|44|33)
+ 1:   abnormal heart morphology [MP:0000266] <22>(27|44) (28|25|19)
0:   abnormal heart layer morphology [MP:0010545] <3>(7|13) (8|7|6)
- 1:   abnormal myocardium layer morphology [MP:0005329] <13>(6|12) (7|7|6)
- 1:   abnormal endocardium morphology [MP:0003974] <3>(1|1) (1|0|0)
- 1:   abnormal subendocardium layer morphology [MP:0010546](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Spectrin repeat0.002634Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.008065Inherited
Nuclear receptor ligand-binding domain0.05086Inherited
SRF-like0.06473Inherited
Fibronectin type III0.1188Inherited
Clavaminate synthase-like0.1491Inherited
"Winged helix" DNA-binding domain0.6725Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Spectrin repeat0.001637Inherited
Protein kinases, catalytic subunit0.002681Inherited
L domain0.009803Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.009803Inherited
ZZ domain0.02204Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.02204Inherited
Nuclear receptor ligand-binding domain0.03772Inherited
Nuclear receptor0.03772Inherited
SRF-like0.04896Inherited
Fibronectin type III0.1119Inherited
Erythroid transcription factor GATA-10.1242Inherited
EGF-type module0.2189Inherited
Forkhead DNA-binding domain0.2285Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Spectrin repeat0.001515Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.004965Inherited
Nuclear receptor ligand-binding domain0.03594Inherited
SRF-like0.04695Inherited
Fibronectin type III0.09154Inherited
Clavaminate synthase-like0.1179Inherited
p53-like transcription factors0.3795Inherited
"Winged helix" DNA-binding domain0.6302Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.0004345Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0006914Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.005894Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.009193Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.009193Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.02099Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.02186Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47473,47473,57850
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.0004345Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.003956Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.009193Inherited
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.04695Inherited
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.04695Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.1221Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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