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Mammalian Phenotype (MP): altered tumor pathology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   mammalian phenotype [MP:0000001] <29>
+ 1:   neoplasm [MP:0002006] <2>(32|37) (38|18|7)
0:   altered tumor pathology [MP:0010639] <4>(9|11) (10|8|5)
- 1:   abnormal tumor morphology [MP:0003448] <3>(5|5) (5|4|2)
- 1:   altered metastatic potential [MP:0000858] <2>(2|2) (2|1|0)
- 1:   abnormal tumor vascularization [MP:0010144](0|0) (0|0|0)
- 1:   tumor regression [MP:0010537](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
p53-like transcription factors0.0003109Direct
Integrin beta tail domain0.0008738Direct
STAT0.0008738Direct
Transcription factor STAT-4 N-domain0.0008738Direct
Metalloproteases ("zincins"), catalytic domain0.003185Inherited
Kringle-like0.02435Inherited
PGBD-like0.06825Inherited
Hemopexin-like domain0.06825Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
p53 tetramerization domain0Direct
p120GAP domain-like0.0001872Direct
STAT DNA-binding domain0.0006117Direct
STAT0.0006117Direct
Integrin beta tail domain0.0006117Direct
Transcription factor STAT-4 N-domain0.0006117Direct
Integrin beta EGF-like domains0.001059Inherited
Matrix metalloproteases, catalytic domain0.02449Inherited
Hemopexin-like domain0.05139Inherited
MMP N-terminal domain0.05139Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
p53-like transcription factors0.0001604Direct
Integrin beta tail domain0.0004729Direct
STAT0.0004729Direct
Transcription factor STAT-4 N-domain0.0004729Direct
ENTH/VHS domain0.0009708Direct
Metalloproteases ("zincins"), catalytic domain0.001856Inherited
Kringle-like0.01624Inherited
Hemopexin-like domain0.04979Inherited
PGBD-like0.04979Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0004729Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.0004729Direct
    53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0.0004729Direct
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.0004729Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0004729Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.03844Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.04979Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.00002293Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.00009346Direct
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.0004729Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0004729Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0004729Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)