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Mammalian Phenotype (MP): abnormal adaptive thermogenesis

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   homeostasis/metabolism phenotype [MP:0005376] <7>(140|174) (149|96|44)
+ 1:   abnormal homeostasis [MP:0001764] <27>(103|129) (113|73|31)
0:   abnormal adaptive thermogenesis [MP:0011019] <3>(6|6) (6|4|2)
- 1:   abnormal response to stress-induced hyperthermia [MP:0010165] <2>(1|1) (1|0|0)
- 1:   impaired adaptive thermogenesis [MP:0011049](3|3) (3|3|2)
- 1:   susceptible to malignant hyperthermia [MP:0020214](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Acyl-CoA dehydrogenase C-terminal domain-like0.00000007702Direct
Acyl-CoA dehydrogenase NM domain-like0.00000007702Direct
STAT0.00006368Direct
Transcription factor STAT-4 N-domain0.00006368Direct
p53-like transcription factors0.004058Inherited
Family A G protein-coupled receptor-like0.01032Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.000000008649Direct
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.000000008649Direct
STAT DNA-binding domain0.00003082Direct
STAT0.00003082Direct
Transcription factor STAT-4 N-domain0.00003082Direct
Rhodopsin-like0.007593Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Acyl-CoA dehydrogenase NM domain-like0.00000003021Direct
Acyl-CoA dehydrogenase C-terminal domain-like0.00000003021Direct
STAT0.00003011Direct
Transcription factor STAT-4 N-domain0.00003011Direct
p53-like transcription factors0.002395Inherited
Family A G protein-coupled receptor-like0.006461Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.00000003021Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.00003011Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.00003011Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.00003011Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.00003011Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.00003011Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)