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Mammalian Phenotype (MP): abnormal circulating triglyceride level

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   homeostasis/metabolism phenotype [MP:0005376] <7>(140|174) (149|96|44)
+ + + 3:   abnormal lipid homeostasis [MP:0002118] <9>(25|29) (29|17|10)
+ + + 3:   abnormal homeostasis [MP:0001764] <27>(103|129) (113|73|31)
+ + 2:   abnormal blood homeostasis [MP:0009642] <23>(63|82) (70|45|21)
+ + 2:   abnormal lipid level [MP:0001547] <16>(24|28) (26|16|10)
+ 1:   abnormal circulating lipid level [MP:0003949] <9>(16|23) (19|13|10)
0:   abnormal circulating triglyceride level [MP:0011969] <2>(6|11) (6|8|5)
- 1:   decreased circulating triglyceride level [MP:0002644] <1>(0|1) (0|0|0)
- 1:   increased circulating triglyceride level [MP:0001552] <1>(4|6) (4|8|5)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Flavoproteins0.000001664Direct
Apolipoprotein A-I0.000005411Direct
STAT0.001517Inherited
Transcription factor STAT-4 N-domain0.001517Inherited
YWTD domain0.06975Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Apolipoprotein A-I0Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.00000253Direct
NADPH-cytochrome p450 reductase-like0.00000253Direct
CAD domain0.00018Direct
STAT DNA-binding domain0.000865Direct
STAT0.000865Direct
Transcription factor STAT-4 N-domain0.000865Direct
Pancreatic lipase, N-terminal domain0.04846Inherited
YWTD domain0.04846Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Flavoproteins0.0000006833Direct
Apolipoprotein A-I0.000002312Direct
STAT0.0008499Direct
Transcription factor STAT-4 N-domain0.0008499Direct
YWTD domain0.05099Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0008499Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.0008499Direct
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.0008499Direct
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.0008499Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0008499Direct
    53474,49723
  • 53474 - alpha/beta-Hydrolases
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0.094Inherited
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.094Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.1356Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.0004321Direct
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.0004321Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0008499Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0008499Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.1356Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)