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Mammalian Phenotype (MP): abnormal total tissue mass

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   growth/size/body region phenotype [MP:0005378] <12>(64|95) (71|47|27)
+ 1:   abnormal body composition [MP:0005451] <5>(20|31) (24|15|9)
0:   abnormal total tissue mass [MP:0012321] <2>(16|26) (19|12|6)
- 1:   decreased total tissue mass [MP:0012322] <1>(6|12) (7|6|3)
- 1:   increased total tissue mass [MP:0012323] <1>(7|7) (7|4|2)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
N-acetylmuramoyl-L-alanine amidase-like0Direct
Guanido kinase N-terminal domain0Direct
FtsH protease domain-like0Direct
p53 tetramerization domain0Direct
Assembly domain of cartilage oligomeric matrix protein0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Flavoproteins0.0006412Direct
FabD/lysophospholipase-like0.0009432Direct
GroEL equatorial domain-like0.05321Inherited
GroEL apical domain-like0.05321Inherited
Acid proteases0.07455Inherited
Family A G protein-coupled receptor-like0.259Inherited
Clathrin adaptor appendage domain0.2667Inherited
Hormone receptor domain0.6184Inherited
STAT0.7949Inherited
Transcription factor STAT-4 N-domain0.7949Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0Direct
Guanido kinase catalytic domain0Direct
Retinoblastoma tumor suppressor domains0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
RUNT domain0Direct
Assembly domain of cartilage oligomeric matrix protein0Direct
NADPH-cytochrome p450 reductase-like0Direct
PAS domain of steroid receptor coactivator 1A, NCo-A10Direct
p53 tetramerization domain0Direct
Guanido kinase N-terminal domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
FtsH protease domain-like0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.0000001741Direct
Phoshoinositide 3-kinase (PI3K) helical domain0.0004507Direct
Phosphate binding protein-like0.002069Inherited
Pepsin-like0.004852Inherited
gamma-adaptin C-terminal appendage domain-like0.01507Inherited
VHS domain0.1324Inherited
DEP domain0.1843Inherited
Rhodopsin-like0.2206Inherited
Hormone receptor domain0.5953Inherited
STAT DNA-binding domain0.7748Inherited
STAT0.7748Inherited
Transcription factor STAT-4 N-domain0.7748Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
FtsH protease domain-like0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
p53 tetramerization domain0Direct
Guanido kinase N-terminal domain0Direct
Assembly domain of cartilage oligomeric matrix protein0Direct
Flavoproteins0.0003424Direct
FabD/lysophospholipase-like0.0005125Direct
Riboflavin synthase domain-like0.0005514Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0005514Direct
ENTH/VHS domain0.01027Inherited
GroEL equatorial domain-like0.03776Inherited
GroEL apical domain-like0.03776Inherited
Acid proteases0.05481Inherited
Family A G protein-coupled receptor-like0.2181Inherited
Clathrin adaptor appendage domain0.2253Inherited
Hormone receptor domain0.5732Inherited
STAT0.7598Inherited
Transcription factor STAT-4 N-domain0.7598Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    52540,140990
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 140990 - FtsH protease domain-like
  • 0Direct
    48034,55931
  • 48034 - Guanido kinase N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 0Direct
    54236,57889
  • 54236 - Ubiquitin-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.0003424Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0005125Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.1696Inherited
    111418,81321
  • 111418 - Hormone receptor domain
  • 81321 - Family A G protein-coupled receptor-like
  • 0.5732Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.7598Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.7598Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.7598Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57850,49599,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0Direct
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0003424Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.7598Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.7598Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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